Skip to Content
MilliporeSigma
All Photos(1)

Documents

1.52064

Supelco

Chromolith® HighResolution RP-8 endcapped

matrix monolithic silica, L × I.D. 100 mm x 4.6 mm HPLC column

Synonym(s):

Chromolith® HighResolution RP-8 endcapped 100-4.6

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
41115700

material

PEEK column

Quality Level

agency

suitable for USP L7

product line

Chromolith®

feature

endcapped

packaging

1 ea of

extent of labeling

11% Carbon loading

parameter

200 bar pressure
45 °C max. temp.

technique(s)

HPLC: suitable
LC/MS: suitable
mass spectrometry (MS): suitable (High)

column L × I.D.

10 cm × 4.6 mm

matrix

monolithic silica

matrix active group

C8 bonding phase

pore size

1.15 μm macroporosity
15 nm mesoporosity

operating pH range

2-7.5

separation technique

reversed phase

storage temp.

no temp limit

General description

Chromolith® columns are made of monolithic silica with a characteristic bimodal pore structure.

Chromolith® HighResolution RP-8 endcapped columns have macropores with 1.15 μm diameter, giving a column efficiency exceeding 140,000 plates/meter. The mesopores are 15 nm (150 Å), the surface modification is octylsilane with full end-capping. Chromolith® HighResolution RP-8 endcapped columns fall under the USP L7 Classification. The column efficiency is comparable to a 2.7 to 3 μm particle size fully porous particulate column.
The column dimension of 100 mm length and 4.6 mm I.D. is the best choice for fast and high-resolution separations of complex compound mixtures.
Chromolith® HighResolution RP-8 endcapped columns are perfectly suitable for LC-MS use.

The revolutionary, monolithic silica with its unique combination of macropores and mesopores enables:
—Rapid separations at very low column back-pressure
—High matrix tolerance, allowing time and cost savings with simplified workflows
—Cost-savings due to extended column lifetimes
—Connection of columns, flow gradients and the use of mobile phases with higher viscosity

Learn more:
Brochure: Race through your Separations on Any System. Chromolith® Monolithic Silica HPLC Columns

All Supelco HPLC Columns, including monolithic Chromolith® columns, are fully compatible to all HPLC and UHPLC Instruments.
Supelco HPLC Products: The Best Choice for Any LC Instrument

Legal Information

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Chromolith® HPLC and UHPLC columns are made from monolithic silica with a bimodal pore structure using sol-gel technology.

Monolithic silica HPLC columns enable high-throughput analysis at low back pressure without loss of separation efficiency or peak capacity.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service