178196
α1-Antichymotrypsin, Human Plasma
Acute-phase protein present at ~45 mg/100 ml in plasma.
Synonym(s):
α1-Antichymotrypsin, Human Plasma, α₁-Achy, α₁-1X, α₁-1X-Glycoprotein
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About This Item
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Quality Level
assay
≥95% (SDS-PAGE)
form
solid
specific activity
≥85%, pH 7.4, 25 °C (using Suc-Ala-Ala-Pro-Phe-pNA as substrate, inhibition of cathepsin G)
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
aqueous buffer: soluble
shipped in
ambient
storage temp.
−20°C
General description
Acute-phase protein present at 45 mg/100 ml in plasma. Specific inhibitor of chymotrypsin-like serine proteinases.
Acute-phase protein present at ~45 mg/100 ml in plasma. Specific inhibitor of chymotrypsin-like serine proteinases. Molecular weight ranges from 65,000-68,000 daltons.
M.W. 65,000-68,000.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Chymotrypsin-like serine proteases
Chymotrypsin-like serine proteases
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Standard Handling (A)
Physical form
Lyophilized from 150 mM NaCl, 20 mM Tris-HCl, pH 7.4.
Preparation Note
Please refer to vial label for lot-specific volume prior to lyophilization.
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for at up to 6 months at -20°C.
Other Notes
Desrochers, P.E., et al. 1992. J. Biol. Chem.267, 5005.
Rayford, A., et al. 1992. J.Neurochem.58, 88.
Travis, J., et al. 1978. Biochemistry17, 5651.
Rayford, A., et al. 1992. J.Neurochem.58, 88.
Travis, J., et al. 1978. Biochemistry17, 5651.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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