178221
α2-Antiplasmin, Human Plasma
A 452-amino acid glycoprotein present in plasma at about 70 µg/ml.
Synonym(s):
α₂-Protease Inhibitor, Primary Plasmin Inhibitor
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.77
Recommended Products
Quality Level
assay
≥95% (SDS-PAGE)
form
solid
specific activity
≥5 IU/mg protein
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
shipped in
ambient
storage temp.
−20°C
General description
A 452-amino acid glycoprotein present in plasma at about 70 µg/ml. Efficiently inhibits the plasminogen activator-induced lysis of fibrin clots. Forms a covalent complex with plasmin and inactivates it.
A 452-amino acid glycoprotein present in plasma at about 70 µg/ml. Efficiently inhibits the plasminogen-activator-induced lysis of fibrin clots. Forms a covalent complex with plasmin and inactivates it.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Plasminogen activator-induced lysis of fibrin clots
Plasminogen activator-induced lysis of fibrin clots
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Standard Handling (A)
Unit Definition
One Inhibitory Unit (I.U.) is defined as the amount of enzyme that will inhibit 1 unit plasmin activity using tosyl-Gly-Pro-Lys-pNA as substrate at 25°C, pH 7.8
Physical form
Lyophilized from 200 mM NaCl, 20 mM Bis-Tris, pH 6.4.
Preparation Note
Please refer to the vial label for the lot-specific reconstitution volume.
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Schaefer, B.M., et al. 1996. Arch. Dermatol. Res. 288, 122.
Aoki, N., et al. 1980. Blood 55, 483.
Saito, H., et al. 1974. Circ. Res.34, 641.
Aoki, N., et al. 1980. Blood 55, 483.
Saito, H., et al. 1974. Circ. Res.34, 641.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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