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Sigma-Aldrich

Calpain Inhibitor V

The Calpain Inhibitor V controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Synonym(s):

Calpain Inhibitor V, Mu-Val-HPh-FMK

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About This Item

Empirical Formula (Hill Notation):
C21H30FN3O4
Molecular Weight:
407.48
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated

color

orange-yellow

solubility

DMSO: 25 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

A potent, cell-permeable, and irreversible inhibitor of calpain.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
calpain
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Mu-Val-HPh-CH₂F (Mu = morpholinoureidyl; HPh = homophenylalanyl)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Analysis Note

single spot by TLC

Other Notes

Esser, R.E., et al. 1994. Arthritis Rheum. 37, 236.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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