218739
Caspase-1 Substrate X, Fluorogenic
A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.
Synonym(s):
Caspase-1 Substrate X, Fluorogenic, Caspase-5 Substrate III, Fluorogenic, Ac-WEHD-AMC
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About This Item
Empirical Formula (Hill Notation):
C38H40N8O11
CAS Number:
Molecular Weight:
784.77
UNSPSC Code:
12352200
NACRES:
NA.54
Recommended Products
Quality Level
assay
≥95% (HPLC)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated
protect from light
solubility
DMSO: 5 mg/mL
fluorescence
λex 365–380 nm
λem 430–460 nm
shipped in
ambient
storage temp.
−20°C
General description
A fluorogenic substrate for detecting caspase-1 (ICE) (excitation maximum: ~365-380 nm; emission maximum: ~430-460 nm).
A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.
Biochem/physiol Actions
Cell permeable: no
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Standard Handling (A)
Sequence
Ac-Trp-Glu-His-Asp-AMC
Other Notes
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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