Skip to Content
MilliporeSigma
All Photos(1)

Documents

219427

Sigma-Aldrich

Cathepsin L Inhibitor III

The Cathepsin L Inhibitor III controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Synonym(s):

Cathepsin L Inhibitor III, Z-FY( t-Bu)-DMK, Z-FY(t-Bu)-DMK

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C31H34N4O5
Molecular Weight:
542.63
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

assay

≥98% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white to light yellow

solubility

DMSO: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

An irreversible inhibitor of Cathepsin L (Cat. No. 219402). About 10,000-fold more effective against cathepsin L than cathepsin S.
An irreversible inhibitor of Cathepsin L (Cat. No. 219402). About 10,000-fold more effective against cathepsin L than cathepsin S.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
Cathepsin L
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Phe-Tyr(t-Bu)-diazomethylketone

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.

Other Notes

Shaw, E., et al. 1993. FEBS Lett. 334, 340.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

E-64 protease inhibitor

Sigma-Aldrich

E3132

E-64

Cong Zeng et al.
bioRxiv : the preprint server for biology (2021-06-09)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible coronavirus responsible for the global COVID-19 pandemic. Herein we provide evidence that SARS-CoV-2 spreads through cell-cell contact in cultures, mediated by the spike glycoprotein. SARS-CoV-2 spike is more efficient

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service