239836
Cyclophilin A Inhibitor
The Cyclophilin A Inhibitor, also referenced under CAS 1186372-20-2, controls the biological activity of Cyclophilin A. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
Synonym(s):
Cyclophilin A Inhibitor
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About This Item
Empirical Formula (Hill Notation):
C21H14ClFN2O2
CAS Number:
Molecular Weight:
380.80
UNSPSC Code:
12352200
NACRES:
NA.77
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Quality Level
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
off-white
solubility
DMSO: 50 mg/mL
shipped in
ambient
storage temp.
−20°C
InChI
1S/C21H14ClFN2O2/c22-16-10-5-11-17(23)18(16)20(26)25-21(27)24-19-14-8-3-1-6-12(14)13-7-2-4-9-15(13)19/h1-11,19H,(H2,24,25,26,27)
InChI key
SFNLLCUAISZNRV-UHFFFAOYSA-N
Warning
Toxicity: Standard Handling (A)
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Tatsuya Tsuda et al.
Journal of pharmacological sciences, 142(3), 109-115 (2019-12-29)
Arterial calcification, a risk factor of cardiovascular events, develops with differentiation of vascular smooth muscle cells (VSMCs) into osteoblast-like cells. Cyclophilin A (CypA) is a peptidyl-prolyl isomerase involved in cardiovascular diseases such as atherosclerosis and aortic aneurysms, and rho-associated protein
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