481486
NF-κB SN50M, Cell-Permeable Inactive Control Peptide
An inactive control for SN50 peptide.
Synonym(s):
NF-κB SN50M, Cell-Permeable Inactive Control Peptide, (AAVALLPAVLLALLAPVQRNGQKLMP)
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About This Item
Empirical Formula (Hill Notation):
C123H215N33O30S
Molecular Weight:
2668.29
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
assay
≥97% (HPLC)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
solubility
water: 5 mg/mL
shipped in
ambient
storage temp.
−20°C
General description
An inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Asn for Lys363 and Gly for Arg364 in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.
An inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Lys363 for Asn and Arg364 for Gly in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.
Biochem/physiol Actions
Cell permeable: no
Primary Target
an inactive control for SN50 peptide
an inactive control for SN50 peptide
Product does not compete with ATP.
Reversible: no
Packaging
Yes
Warning
Toxicity: Standard Handling (A)
Sequence
H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Asn-Gly-Gln-Lys-Leu-Met-Pro-OH
Physical form
Supplied as a trifluoroacetate salt.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid/freeze thaw cycles of solutions.
Other Notes
Lin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.
Legal Information
Sold under license of U.S. Patents 5,807,746 and 6,043,339 for research use only. Licenses for commercial manufacture, commercial use, diagnostics, or therapeutics may be obtained by contacting Vanderbilt University, Nashville, Tennessee.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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