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495417-M

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N-Oleoyl Ethanolamine

A potent inhibitor of the ceramidase found in human kidney and cerebellum.

Synonym(s):

N-Oleoyl Ethanolamine, N-2-Hydroxyethyl-9(Z)-octadecenamide, AC Inhibitor I, Acid Ceramidase Inhibitor I, OEA

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About This Item

Empirical Formula (Hill Notation):
C20H39NO2
CAS Number:
Molecular Weight:
325.53
MDL number:
UNSPSC Code:
12352211

Quality Level

assay

≥98% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

chloroform: 5 mg/mL
ethanol: 5 mg/mL
methanol: 5 mg/mL

storage temp.

−20°C

InChI

1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-

InChI key

BOWVQLFMWHZBEF-KTKRTIGZSA-N

General description

A potent inhibitor of the ceramidase found in human kidney and cerebellum. A specific inhibitor of acid ceramidase (IC50 ~ 500 µM).
A potent inhibitor of the ceramidase found in human kidney and cerebellum. Blocks the conversion of ceramide to sphingosine. A specific inhibitor of acid ceramidase (IC50 ~ 500 µM).

Biochem/physiol Actions

Primary Target
Acid ceramidase
Target IC50: ~ 500 µM against acid ceramidase

Warning

Toxicity: Standard Handling (A)

Other Notes

Pahan, K., et al. 1998. J. Biol. Chem. 273, 2591.
Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
Sugita, M., et al. 1975. Biochim. Biophys. Acta398, 125.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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