561300
E-Selectin, Human, Recombinant, CHO Cells
Synonym(s):
CD62E, ELAM-1
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Recommended Products
assay
≥95% (SDS-PAGE)
Quality Level
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
<1 EU/μg Endotoxin (EU/μg of E-Selectin)
shipped in
wet ice
storage temp.
−20°C
General description
Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands such as SLex found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.
Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands, such as sialyl Lewis x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.
Biochem/physiol Actions
Shown to bind to E-selectin ligands on U937 cells.
Warning
Toxicity: Standard Handling (A)
Physical form
Lyophilized from Dulbecco′s PBS with stabilizer.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Reconstitute to 1 mg/ml with sterile H₂O.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
wgk_germany
WGK 2
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service