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8.00592

Sigma-Aldrich

Phthalic anhydride

for synthesis

Synonym(s):

Phthalic anhydride

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About This Item

Empirical Formula (Hill Notation):
C8H4O3
CAS Number:
Molecular Weight:
148.12
MDL number:
UNSPSC Code:
12352115
EC Index Number:
201-607-5

vapor pressure

<0.01 hPa ( 20 °C)

Quality Level

form

crystals

autoignition temp.

580 °C

potency

1530 mg/kg LD50, oral (Rat)
>3160 mg/kg LD50, skin (Rabbit)

expl. lim.

1.7-10.5 % (v/v)

pH

2 (20 °C, 6 g/L in H2O)

bp

285 °C/1013 hPa

mp

131 °C

transition temp

flash point 152 °C

solubility

6 g/L (slow decomposition)

density

1.527 g/cm3 at 20 °C

bulk density

500‑700 kg/m3

storage temp.

no temp limit

InChI

1S/C8H4O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h1-4H

InChI key

LGRFSURHDFAFJT-UHFFFAOYSA-N

Application

<ul>
<li><strong>Antibacterial and cytotoxic activity of chitosan derivatives:</strong>Phthalic anhydride-modified chitosan derivatives exhibit significant antibacterial and cytotoxic properties, suggesting their potential application in medical and pharmaceutical products (Sousa et al., 2024).</li>
<li><strong>Heterodinuclear Polymerization Catalysts:</strong> Research identified Al(III)/K(I) polymerization catalysts that utilize phthalic anhydride for producing high-quality polyester polyols, offering advancements in polymer synthesis technology (Shellard et al., 2024).</li>
<li><strong>Advanced epoxy vitrimers:</strong> Phthalic anhydride was used in the design and synthesis of advanced epoxy vitrimers with enhanced glass transition temperatures, important for applications requiring high-performance thermoset polymers (Dai et al., 2023).</li>
<li><strong>Sustainable alkyd resins:</strong> The utilization of phthalic anhydride in the production of alkyd resins from bio-based resources represents a significant move towards more sustainable and environmentally friendly coating applications (Dizman and Cerrahoglu Ka and ccedil;akgil, 2023).</li>
</ul>

Analysis Note

Assay (morpholine method): ≥ 98,0 %(m)
Melting range (lower value): ≥ 129 °C
Melting range (upper value): ≤ 133 °C
Identity (IR): conforms

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

8A - Combustible, corrosive hazardous materials

wgk_germany

WGK 1

flash_point_f

305.6 °F - DIN 51758

flash_point_c

152 °C - DIN 51758


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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