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8.04324

Sigma-Aldrich

1,1,1,3,3,3-Hexamethyldisilazane

for synthesis

Synonym(s):

1,1,1,3,3,3-Hexamethyldisilazane, Bis(trimethylsilyl)amine, HMDS

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About This Item

Empirical Formula (Hill Notation):
C6H19NSi2
CAS Number:
Molecular Weight:
161.39
MDL number:
UNSPSC Code:
12352103
EC Index Number:
213-668-5
NACRES:
NA.22

vapor pressure

20 hPa ( 20 °C)

Quality Level

assay

≥98% (GC)

form

liquid

autoignition temp.

325 °C

potency

847 mg/kg LD50, oral (Rat)
550 mg/kg LD50, skin (Rabbit)

expl. lim.

0.8-25.9 % (v/v)

kinematic viscosity

0.9 cSt(25 °C)

bp

126 °C/1013 mbar

mp

-82 °C

transition temp

flash point 15 °C

density

0.78 g/cm3 at 20 °C

storage temp.

2-30°C

InChI

1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3

InChI key

FFUAGWLWBBFQJT-UHFFFAOYSA-N

Application

  • Handling and Safety Protocols of 1,1,1,3,3,3-Hexamethyldisilazane: This article presents a comprehensive overview of the handling and safety protocols associated with 1,1,1,3,3,3-Hexamethyldisilazane, emphasizing its applications in various industrial and pharmaceutical contexts. The study provides insights on its safe usage, particularly focusing on its role as a silylation agent in analytical chemistry and as a precursor in chemical vapor deposition processes (Toxicol Ind Health, 2019).

Analysis Note

Assay (GC, area%): ≥ 98 %
Density (d 20 °C/ 4 °C): 0.774 - 0.775
Identity (IR): passes test

pictograms

FlameSkull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

52.5 °F - closed cup

flash_point_c

11.4 °C - closed cup


Certificates of Analysis (COA)

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