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8.21111

Sigma-Aldrich

2-Thiazoline-2-thiol

for synthesis

Synonym(s):

2-Thiazoline-2-thiol, 2-Mercaptothiazoline

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About This Item

Empirical Formula (Hill Notation):
C3H5NS2
CAS Number:
Molecular Weight:
119.21
MDL number:
UNSPSC Code:
12352113
EC Index Number:
202-512-1

Quality Level

form

powder

potency

300 mg/kg LD50, oral (Rat)

pH

6-7 (20 °C, 10 g/L in H2O)

mp

101-106 °C

storage temp.

2-30°C

InChI

1S/C3H5NS2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)

InChI key

WGJCBBASTRWVJL-UHFFFAOYSA-N

Application

  • Inducing apoptosis in melanoma cells: A study described a ruthenium(II) complex with 2-mercaptothiazoline ligand inducing selective cytotoxicity by causing DNA damage and apoptosis specifically in melanoma cells, highlighting its potential as a therapeutic agent in oncology (de Melo et al., 2024).
  • Antimicrobial and synergistic activities: Thiazoline derivatives, including compounds related to 2-mercaptothiazoline, were studied for their antimicrobial and synergistic effects with conventional antibiotics against multidrug-resistant Staphylococcus aureus, presenting a potential strategy for enhancing antibiotic efficacy (Khan et al., 2020).
  • Antimicrobial investigation of metal complexes: The antimicrobial properties of Cd(II) and Sn(II) complexes with 2-mercaptothiazoline were evaluated, underscoring the compound′s role in enhancing the bioactivity of metal-based therapeutics (Gaber et al., 2021).

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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