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8.22324

Supelco

1,2-Propanediol

EMPLURA®

Synonym(s):

1,2-Propanediol, 1,2-Propylene glycol

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About This Item

Linear Formula:
CH3CH(OH)CH2OH
CAS Number:
Molecular Weight:
76.09
MDL number:
UNSPSC Code:
12352104
EC Index Number:
200-338-0

vapor pressure

0.11 hPa ( 20 °C)

Quality Level

product line

EMPLURA®

assay

≥99% (GC)

form

liquid

autoignition temp.

371 °C

potency

19400-36000 mg/kg LD50, oral (Rat)
20800 mg/kg LD50, skin (Rabbit)

expl. lim.

2.4-17.4 % (v/v)

impurities

≤0.2% Water

refractive index

n20/D 1.43

pH

6-8 (20 °C, 100 g/L in H2O)

bp

188 °C/1013 hPa

mp

-59 °C

transition temp

flash point 99 °C

density

1.04 g/cm3 at 20 °C

storage temp.

2-30°C

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

Application


  • (1)H-NMR metabolomics investigation of CSF from children with HIV reveals altered neuroenergetics due to persistent immune activation.: This research uses 1,2-Propanediol in metabolic profiling to study CSF in children with HIV, identifying neuroenergetic alterations due to persistent immune activation (Thirion et al., 2024).

  • Insight into the influence of natural deep eutectic solvents on the extraction of phenolic compounds from poplar type propolis: Composition and in vitro biological activity.: The study explores using 1,2-Propanediol-based deep eutectic solvents for extracting phenolic compounds from propolis, assessing their composition and biological activity (Trusheva et al., 2024).

  • In Silico-Assisted Isolation of trans-Resveratrol and trans-e-Viniferin from Grapevine Canes and Their Sustainable Extraction Using Natural Deep Eutectic Solvents (NADES).: This publication discusses the application of 1,2-Propanediol in the green chemistry extraction of valuable compounds from grapevines using computational and experimental methods (Kiene et al., 2023).

  • Untargeted metabolomics provide new insights into the implication of Lactobacillus helveticus strains isolated from natural whey starter in methylglyoxal-mediated browning.: Research utilizing 1,2-Propanediol in metabolomic studies to understand the metabolic pathways influenced by Lactobacillus strains in dairy products (Galimberti et al., 2023).

  • Milk oligosaccharide-driven persistence of Bifidobacterium pseudocatenulatum modulates local and systemic microbial metabolites upon synbiotic treatment in conventionally colonized mice.: A study focusing on the role of 1,2-Propanediol in modulating microbial metabolites through synbiotic treatments, impacting gut microbiota and systemic health (Larke et al., 2023).


Analysis Note

Purity (GC): ≥ 99.0 %
Identity (IR): conforms
Density (d 20 °C/ 4 °C): 1.036 - 1.037
Water: ≤ 0.20 %

Legal Information

EMPLURA is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

219.2 °F - closed cup

flash_point_c

104 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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