8.40124
Span® 85
for synthesis
Synonym(s):
Span® 85, Sorbitan trioleate, (Z,Z,Z)-Sorbitan tri-9-octadecenoate
About This Item
Recommended Products
vapor pressure
<1.4 hPa ( 20 °C)
Quality Level
form
liquid
potency
39800 mg/kg LD50, oral (Rat)
kinematic viscosity
120 cSt(40 °C)
transition temp
flash point 225 °C
solubility
insoluble <0.001 g/L
density
0.95 g/cm3 at 20 °C
storage temp.
2-30°C
InChI
1S/C60H108O8/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56(62)65-53-55(67-57(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2)60-59(54(61)52-66-60)68-58(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3/h25-30,54-55,59-61H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27-/t54-,55?,59+,60-/m1/s1
InChI key
PRXRUNOAOLTIEF-XDTJCZEISA-N
Application
- Macromolecular Stabilization: Span® 85 is used as a stabilizer for the preparation of PMMA colloidal particles in nonpolar media, proving effective in maintaining stability under various conditions, crucial for industrial applications in coatings and advanced materials manufacturing (Liu et al., 2022).
- Enhanced Nanoemulsion Systems: It plays a critical role in the formation of aerosolized nanoemulsion systems encapsulating docetaxel and curcumin, utilized in cancer therapy to improve therapeutic outcomes through enhanced drug delivery mechanisms (Abdul Rahman et al., 2020).
- Skin Protection Formulations: Span® 85 is integral in the formulation and clinical assessment of microemulsion-based hydrogels for UV protection, demonstrating its utility in skincare products by enhancing sun protection factor and skin compatibility (Ebrahimi et al., 2019).
- Transdermal Drug Delivery: This surfactant is utilized in tailoring novel soft nano-vesicles, known as ′Flexosomes′, to enhance transdermal drug delivery, which is pivotal for non-invasive therapeutic applications and improving patient compliance (Mansour et al., 2019).
Analysis Note
Saponification value: 170 - 190
Identity (IR): passes test
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.
Legal Information
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
437.0 °F
flash_point_c
225 °C
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service