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Sigma-Aldrich

Fmoc-Asn(Trt)-OPfp

Novabiochem®

Synonym(s):

Fmoc-Asn(Trt)-OPfp, N-α-Fmoc-N-β-trityl-L-asparagine pentafluorophenyl ester

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About This Item

Empirical Formula (Hill Notation):
C44H31F5N2O5
CAS Number:
Molecular Weight:
762.72
UNSPSC Code:
12352209
NACRES:
NA.22

Quality Level

product line

Novabiochem®

assay

≥97.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amide

storage temp.

15-25°C

InChI

1S/C44H31F5N2O5/c45-36-37(46)39(48)41(40(49)38(36)47)56-42(53)34(50-43(54)55-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)24-35(52)51-44(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,50,54)(H,51,52)/t34-/m0/s1

InChI key

YSONQVIVMGOLBG-UMSFTDKQSA-N

General description

Pre-formed pentafluorophenyl ester for coupling of asparagine amino-acid residues by Fmoc SPPS. Use enables bromophenol blue monitoring of amide bond formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-12-1538

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in dioxan): -9.0 - -5.0 °
Purity (TLC (0004)): <2% DCU
Assay (HPLC, area%): ≥ 97.0% (a/a)
Solubility (0.5 mmole in 3 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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