AB1569
Anti-Dopa Decarboxylase Antibody
Chemicon®, from rabbit
Synonym(s):
Anti-AADC
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
canine, bovine, rat, guinea pig, human, sheep
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... CDNF(441549)
Specificity
DOPA Decarboxylase (DDC). Reacts with a single band of ~55 kDa by Western blot.
Immunogen
Recombinant bovine DDC expressed in E. coli and purified from inclusion bodies.
Application
Detect Dopa Decarboxylase using this Anti-Dopa Decarboxylase Antibody validated for use in IH & WB.
Immunoblotting: 1:500-1:1,000
Immunohistochemistry using formaldehyde-fixed brain sections.
Optimal working dilutions must be determined by the end user.
Immunohistochemistry using formaldehyde-fixed brain sections.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neuronal & Glial Markers
Neurotransmitters & Receptors
Neuronal & Glial Markers
Physical form
Affinity purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.
Storage and Stability
Maintain at -20 to -80°C in undiluted aliquots for up to six months after date of receipt. Store in a NON-self-defrosting freezer. Avoid repeated freeze-thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Lack of regulation of aromatic L-amino acid decarboxylase in intact bovine chromaffin cells.
Jack C Waymire, John W Haycock
Journal of Neurochemistry null
Branden J Stansley et al.
Neuropharmacology, 67, 243-251 (2012-12-01)
L-dopa is a precursor for dopamine synthesis and a mainstay treatment for Parkinson's disease. However, l-dopa therapy is not without side effects that may be attributed to non-dopaminergic mechanisms. Synthesized dopamine can be neurotoxic through its enzymatic degradation by monoamine
Increased expression of VMAT2 in dopaminergic neurons during nicotine withdrawal.
Anne-Marie Duchemin,Hailing Zhang,Norton H Neff,Maria Hadjiconstantinou
Neuroscience Letters null
Innate immunity in insects: surface-associated dopa decarboxylase-dependent pathways regulate phagocytosis, nodulation and melanization in medfly haemocytes.
Sideri, M; Tsakas, S; Markoutsa, E; Lampropoulou, M; Marmaras, VJ
Immunology null
Jennifer M King et al.
Life sciences, 89(17-18), 638-643 (2011-08-30)
l-3,4-Dihydroxyphenylalanine (L-DOPA) is the most effective symptomatic treatment for Parkinson's disease (PD), but PD patients usually experience a successful response to L-DOPA therapy followed by a progressive loss of response. L-DOPA efficacy relies on its decarboxylation by aromatic l-amino acid
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