AB5559
Anti-GABA A Receptor γ2 Antibody, cytoplasmic loop
Chemicon®, from rabbit
Synonym(s):
Anti-CAE2, Anti-DEE74, Anti-ECA2, Anti-EIEE74, Anti-FEB8, Anti-GEFSP3
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... GABRG2(2566)
Specificity
GABAA receptor gamma2 subunit. Reacts with the ~44-47kDa gamma2 subunit of the GABAA receptor in rat brain membrane fractions.
Immunogen
Epitope: cytoplasmic loop
MBP fusion protein from the cytosolic loop of rat GABAA receptor gamma2 subunit.
Application
Anti-GABA A Receptor γ2 Antibody, cytoplasmic loop detects level of GABA A Receptor γ2 & has been published & validated for use in IP & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Western blot: 1:1,000
Immunopreciptation: The antibody will immunoprecipitate 49% of all GABAA receptors in dodecylsulfate extracts of rat forebrains (150 μL) using 15 μg of antibody.
Optimal working dilutions must be determined by the end user.
Immunopreciptation: The antibody will immunoprecipitate 49% of all GABAA receptors in dodecylsulfate extracts of rat forebrains (150 μL) using 15 μg of antibody.
Optimal working dilutions must be determined by the end user.
Physical form
Affinity purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, with 150 mM NaCl, 100 μg/mL BSA and 50% glycerol. Approximate concentration is 0.2 mg/mL.
Storage and Stability
Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
wgk_germany
WGK 2
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Tumor necrosis factor alpha mediates GABA(A) receptor trafficking to the plasma membrane of spinal cord neurons in vivo.
Stuck, ED; Christensen, RN; Huie, JR; Tovar, CA; Miller, BA; Nout, YS; Bresnahan et al.
Neural Plast. null
Yan Li et al.
Frontiers in aging neuroscience, 9, 212-212 (2017-07-18)
A decline in cardiovascular modulation is a feature of the normal aging process and associated with cardiovascular diseases (CVDs) such as hypertension and stroke. Exercise training is known to promote cardiovascular adaptation in young animals and positive effects on motor
GABAA receptors are expressed and facilitate relaxation in airway smooth muscle.
Mizuta, K; Xu, D; Pan, Y; Comas, G; Sonett, JR; Zhang, Y; Panettieri, RA; Yang, J; Emala, CW
American Journal of Physiology. Lung Cellular and Molecular Physiology null
Stoichiometry and assembly of a recombinant GABAA receptor subtype.
Tretter, V, et al.
The Journal of Neuroscience, 17, 2728-2737 (1997)
Shimian Qu et al.
Brain communications, 2(1), fcaa028-fcaa028 (2020-05-30)
The Lennox-Gastaut syndrome is a devastating early-onset epileptic encephalopathy, associated with severe behavioural abnormalities. Its pathophysiology, however, is largely unknown. A de novo mutation (c.G358A, p.D120N) in the human GABA type-A receptor β3 subunit gene (GABRB3) has been identified in
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service