Skip to Content
MilliporeSigma
All Photos(1)

Documents

ABF13

Sigma-Aldrich

Anti-Interleukin-10 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, human

technique(s)

western blot: suitable

NCBI accession no.

NP_034678

UniProt accession no.

P18893

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... IL10(3586)

Related Categories

General description

Interleukin-10 (IL-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF) is an 18.7 kDa protein of 160 amino acid residues that shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI. IL-10 down regulates the expression of Th1 cytokines, major histocompatibility complex class II antigens, and costimulatory molecules on macrophages. It also enhaces B cell survival, proliferation, and antibody production. Knockout studies suggest that IL-10 is an immunoregulator in the intestinal tract.

Immunogen

GST-tagged recombinant protein corresponding to mouse Interleukin-10.

Application

Detect Interleukin-10 using this Anti-Interleukin-10 Antibody validated for use in WB.

Quality

Evaluated by Western Blot in mouse Interleukin-10 recombinant protein.

Western Blot Analysis: 0.01 µg/mL of this antibody detected Interleukin-10 on 10 µg of mouse Interleukin-10 recombinant protein.

Target description

~18 kDa observed.

Analysis Note

Control
Mouse Interleukin-10 recombinant protein

Not finding the right product?  

Try our Product Selector Tool.

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Exercise ameliorates high fat diet induced cardiac dysfunction by increasing interleukin 10.
Kesherwani, V; Chavali, V; Hackfort, BT; Tyagi, SC; Mishra, PK
Frontiers in Physiology null

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service