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ABS568

Sigma-Aldrich

Anti-RBP4 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Retinol-binding protein 4, Plasma retinol-binding protein, PRBP, RBP, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176)

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

western blot: suitable

NCBI accession no.

NP_006735

UniProt accession no.

P02753

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... RBP4(5950)

General description

The role of the protein retinol binding protein 4 (RBP4) has always been understood to be involvement in the transport of vitamin A. However, research has demonstrated that blood levels of RBP4 is closely linked with the development of insulin resistance, which predisposes individuals to type 2 diabetes and is a major risk factor for cardiovascular disease. In addition higher levels of RBP4 were closely associated with other components of metabolic syndrome, including increased body mass index, waist-to-hip ratio, serum triglyceride levels and systolic blood pressure, as well as decreased HDL levels. Further investigations indicate that RBP4 may be a useful biomarker in identifying a predisposition to type 2 diabetes and measuring therapeutic improvement.

Immunogen

Recombinant protein corresponding to human RBP4.

Application

Anti-RBP4 Antibody is a highly specific rabbit polyclonal antibody, that targets Retinol binding protein 4 & has been tested in western blotting.
Research Category
Signaling
Research Sub Category
Metabolic Hormones & Receptors
Western Blotting Analysis: 2.0 µg/mL from a representative lot detected RBP4 in 10 µg of human spleen, thymus, ovary and testis tissue lysates.

Quality

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected RBP4 in 10 µg of human liver tissue lysate.

Target description

~23 kDa observed

Linkage

Replaces: MABN1095

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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