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MAB1892

Sigma-Aldrich

Anti-Fibronectin Antibody, gelatin binding domain, clone IST-10

clone IST-10, Chemicon®, from mouse

Synonym(s):

Anti-CIG, Anti-ED-B, Anti-FINC, Anti-FN, Anti-FNZ, Anti-GFND, Anti-GFND2, Anti-LETS, Anti-MSF, Anti-SMDCF

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

IST-10, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG1κ

NCBI accession no.

NM_002026.2
NM_054034.2
NM_212474.1
NM_212475.1
NM_212476.1
NM_212478.1
NM_212482.1

UniProt accession no.

P02751

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... FN1(2335)
mouse ... Fn1(14268)

Specificity

Recognizes an epitope contained within the gelatin binding domain of human fibronectin.

Immunogen

Epitope: gelatin binding domain

Application

Anti-Fibronectin Antibody, gelatin binding domain, clone IST-10 is an antibody against Fibronectin for use in WB, IH.
Immunohistochemistry

Immunoblotting: non-reducing conditions

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

Physical form

Format: Purified
Purified immunoglobulin in 0.02M phosphate buffer, 0.25M sodium chloride, 0.1% sodium azide, pH 7.6

Storage and Stability

Maintain between 2 and 8°C .

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jane Sottile et al.
American journal of physiology. Cell physiology, 293(6), C1934-C1946 (2007-10-12)
Communication between cells and the extracellular matrix (ECM) is critical for regulation of cell growth, survival, migration, and differentiation. Remodeling of the ECM can occur under normal physiological conditions, as a result of tissue injury, and in certain pathological conditions.
Migration-stimulating factor: a genetically truncated onco-fetal fibronectin isoform expressed by carcinoma and tumor-associated stromal cells.
Seth L Schor, Ian R Ellis, Sarah J Jones, Robin Baillie, Kanjula Seneviratne et al.
Cancer Research null
Preferential recognition of a fragment species of osteoarthritic synovial fluid fibronectin by antibodies to the alternatively spliced EIIIA segment.
J H Peters, S Carsons, K Kalunian, S McDougall, M Yoshida, F Ko, M van der Vliet-Hristova, T J Hahn
Arthritis and Rheumatism null
Definition of the native and denatured type II collagen binding site for fibronectin using a recombinant collagen system.
An, B; Abbonante, V; Yigit, S; Balduini, A; Kaplan, DL; Brodsky, B
The Journal of Biological Chemistry null

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