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MABN314

Sigma-Aldrich

Anti-Gamma-synuclein (SNCG), clone 3D2.1 Antibody

clone 3D2.1, from mouse

Synonym(s):

Gamma-synuclein, Breast cancer-specific gene 1 protein, Persyn, Synoretin, SR

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

3D2.1, monoclonal

species reactivity

human

technique(s)

western blot: suitable

isotype

IgG1κ

NCBI accession no.

NP_003078

UniProt accession no.

O76070

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... SNCG(6623)

General description

Gamma-synuclein is one four proteins in the synuclein family, Gamma-synuclein appears to play a role in neurofilament network integrity and interaction. Gamma synuclein is important for axonal architecture and maintenance and the protein interacts with both the MAPK and ELK-1 signaling networks. Gamma synuclein is a cytoplasmically associated protein that is also strongly associated with cytoskeletal elements. During cell division, gamma synuclein is associated with the poles of the spindle and interruption causes defects in cytokinesis. Gamma synuclein is highly expressed in the brain but can also be found expressed in the heart, skeletal muscle, colon, and gonads. Gamma synuclein is also expressed in many invasive cancers.

Immunogen

GST-tagged recombinant protein corresponding to human Gamma-synuclein (SNCG).

Application

Research Category
Neuroscience
Research Sub Category
Developmental Signaling
This Anti-Gamma-synuclein (SNCG), clone 3D2.1 Antibody is validated for use in Western Blotting for the detection of Gamma-synuclein (SNCG).

Quality

Evaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Gamma-synuclein (SNCG) in 10 µg of human cortex tissue lysate.

Target description

~15 kDa observed

Physical form

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to lot specific datasheet.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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