SCT085
BioTracker™ MemBright 640 Live Cell Dye
Synonym(s):
Live cell imaging probe, Live cell membrane probe, far red
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About This Item
UNSPSC Code:
41106514
Recommended Products
mol wt
observed mol wt 1396.4 kDa
Quality Level
packaging
vial of 50 μL
manufacturer/tradename
Millipore
growth mode
N/A
technique(s)
cell based assay: suitable
flow cytometry: suitable
detection method
fluorometric
shipped in
cooler
storage temp.
−20°C
General description
The BioTracker™ Membright-640 live cell dye is a “turn-on” fluorescence probe emitting in the far red spectrum for the imaging of plasma membranes of live cells.
Probes specific for the plasma membrane are fundamental tools for marking cell boundaries. Membright probes use a unique mechanism, existing in a self-quenched nanoparticle state. On contact and propagation within the cell membrane, the probe becomes fluorogenic, demonstrating remarkably high signal-to-background ratio. These live cell membrane probes are compatible with two-photon imaging, superresolution imaging, and are suitable for use in live or fixed cells. Their exceptional photostability and lack of cytotoxicity make Membright probes optimal for long-term imaging studies. The key characteristics of these plasma membrane probes permit use in a broad spectrum of fluorescence microscopy applications, and in flow cytometry.
Spectral Properties
Fluorescence images obtained by λex = 640 nm and emission range of 640-800 nm.
Reference
Collot M et al. MemBright: A family of fluorescent membrane probes for advanced cellular imaging and neuroscience. Cell Chem. Biol. 2019, 26:600-614
Probes specific for the plasma membrane are fundamental tools for marking cell boundaries. Membright probes use a unique mechanism, existing in a self-quenched nanoparticle state. On contact and propagation within the cell membrane, the probe becomes fluorogenic, demonstrating remarkably high signal-to-background ratio. These live cell membrane probes are compatible with two-photon imaging, superresolution imaging, and are suitable for use in live or fixed cells. Their exceptional photostability and lack of cytotoxicity make Membright probes optimal for long-term imaging studies. The key characteristics of these plasma membrane probes permit use in a broad spectrum of fluorescence microscopy applications, and in flow cytometry.
Spectral Properties
Fluorescence images obtained by λex = 640 nm and emission range of 640-800 nm.
Reference
Collot M et al. MemBright: A family of fluorescent membrane probes for advanced cellular imaging and neuroscience. Cell Chem. Biol. 2019, 26:600-614
Application
Purity: > 98% confirmed by HPLC, HNMR, LC-MS and elemental analysis.
Features and Benefits
Far red fluorescent probe for efficient, selective labeling of the plasma membrane in live cells. Suitable for superresolution microscopy.
Physical form
Blue solution
Storage and Stability
Store long term at -20°C, protected from light.
Other Notes
Live cell fluorescent imaging, flow cytometry
Legal Information
BioTracker is a trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
Certificates of Analysis (COA)
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