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SCT261

Sigma-Aldrich

BioTracker™ Mitochondrial Lipid Peroxide Live Cell Ferroptosis Indicator

Human

Synonym(s):

mitochondria live cell probe, mitochondrial ferroptosis live cell probe, mitochondrial lipid peroxidation probe

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About This Item

UNSPSC Code:
41106514
NACRES:
NA.47

product name

BioTracker™ Mitochondrial Lipid Peroxide Live Cell Ferroptosis Indicator,

biological source

human

Quality Level

100

packaging

vial of 15 μg

manufacturer/tradename

Millipore

technique(s)

cell culture | stem cell: suitable
flow cytometry: suitable

shipped in

2-8°C

storage temp.

2-8°C

General description

This product is a cell-membrane-permeable, perylene-based probe for use in live cell cultures. The compound specifically localizes in mitochondria due to the triphenylphosphonium moiety. It is therefore optimal for monitoring lipid peroxidation in ferroptosis.IMPORTANT APPLICATION NOTES: Prepare 0.1 mM stock solution by dissolving the 5ug of SCT261 in 50 uL DMSO. Lyophilized probe may be difficult to see, confirm with yellow color of working solution. Protect solution from light and use within the same day. Dilute with Hanks′ HEPES buffer to prepare 0.1 to 0.5 uM working solution.SPECTRAL PROPERTIESλex: 452 nmλem: 470 nmSuitable for use with FITC/GFP laser or filter

Features and Benefits

This probe is designed for the detection of lipid peroxidation in live cells by fluorescent microscopy or flow cytometry.

Target description

BioTracker™ Mitochondrial Lipid Peroxide Live Cell Ferroptosis Indicator is a cell-membrane-permeable, perylene-based dye. It specifically localizes to mitochondria via introduction of the triphenylphosphonium moiety. SCT261 is used to monitor lipid peroxidation in ferroptosis research.With excitation and emission wavelengths of 452 nm and 470 nm respectively, this probe can be applied for lipophilic peroxide imaging in living cells.

Storage and Stability

Store BioTracker™ Mitochondrial Lipid Peroxide Live Cell Ferroptosis Indicator at 2 - 8 °C, protected from light.

Other Notes

Live cell probe for fluorescent detection of lipid peroxidation in mitochondria by fluorescence microscopy or flow cytometry. SCT261 is an essential tool for ferroptosis research in live cell models.

Legal Information

BioTracker is a trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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