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Supelco

Mangiferin

analytical standard

Synonym(s):

1,3,6,7-Tetrahydroxyxanthone C2-β-D-glucoside, Chinomin, Chinonin, Shamimin

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About This Item

Empirical Formula (Hill Notation):
C19H18O11
CAS Number:
4773-96-0
Molecular Weight:
422.34
MDL number:
MFCD00075656
UNSPSC Code:
85151701
PubChem Substance ID:
329748228
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥98.0% (TLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3Oc4cc(O)c(O)cc4C(=O)c3c2O

InChI

1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1

InChI key

AEDDIBAIWPIIBD-ZJKJAXBQSA-N

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General description

Mangiferin is a xanthone glucoside and a naturally occurring polyphenol found abundantly in the plants of genus Mangifera particularly Mangifera indica L. and also in some medicinal herbs. Mangiferin exhibits antioxidant, antiviral, antitumor, anti-inflammatory and gene-regulatory effects and is considered to be of high research interest due to its therapeutic properties.

Application

Mangiferin may be used as an analytical standard for the determination of the analyte in rat plasma, traditional Chinese medicines and honeybush tea (Cyclopia spp.) by chromatography based techniques.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: hypericum

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H300

Hazard Classifications

Acute Tox. 1 Oral

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Ronghua Dai et al.
Journal of chromatographic science, 42(4), 207-210 (2004-05-25)
High-performance liquid chromatography is employed to determine the contents of six marker components such as mangiferin, jateorrhizine, palmatine, berberine, cinnamic acid, and cinnamaldehyde in the traditional Chinese medicinal preparation Zi-Shen pill. The separation is performed on a C(18) column by
High-performance liquid chromatographic method for the determination of mangiferin, likviritin and dihydroquercetin in rat plasma and urine
Geodakyan SV, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 577(2), 371-375 (1992)
Reversed-phase HPLC determination of mangiferin, isomangiferin and hesperidin in Cyclopia and the effect of harvesting date on the phenolic composition of C. genistoides
Joubert E, et al.
European Food Research and Technology, 216(3), 270-273 (2003)
A Vyas et al.
Mini reviews in medicinal chemistry, 12(5), 412-425 (2012-02-07)
Mango tree, Mangifera indica, has been cultivated in India and several other tropical countries for centuries, and it is a good source of compound 'mangiferin'. Mangiferin's xanthonoid structure with C-glucosyl linkage and polyhydroxy component is believed to be crucial for
Adam Matkowski et al.
Mini reviews in medicinal chemistry, 13(3), 439-455 (2012-11-30)
Mangiferin is a plant natural polyphenol of C-glycosylxanthone structure and various pharmacological activities. It can be found in many plant species, among which the mango tree (Mangifera indica) is one of the primary sources. Mangiferin is also present in some
View All Related Papers

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