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Supelco

4-Aminoantipyrine

for spectrophotometric det. of H2O2 and phenols, ≥98.0%

Synonym(s):

4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, Ampyrone

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About This Item

Empirical Formula (Hill Notation):
C11H13N3O
CAS Number:
Molecular Weight:
203.24
Beilstein/REAXYS Number:
181635
EC Number:
MDL number:
UNSPSC Code:
41116105
PubChem Substance ID:
NACRES:
NA.21

Quality Level

assay

≥98.0% (NT)
≥98.0%

quality

for spectrophotometric det. of H2O2 and phenols

technique(s)

UV/Vis spectroscopy: suitable
photometry: suitable

mp

105-110 °C (lit.)
108-110 °C

solubility

H2O: 0.1 g/mL, clear to slightly hazy

SMILES string

CN1N(c2ccccc2)C(=O)C(N)=C1C

InChI

1S/C11H13N3O/c1-8-10(12)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,12H2,1-2H3

InChI key

RLFWWDJHLFCNIJ-UHFFFAOYSA-N

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Application


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  • Pharmacokinetics-Based Pediatric Dose Evaluation and Optimization Using Saliva - A Case Study.: This paper presents a methodological innovation using saliva samples to optimize pediatric dosing of medications, which could revolutionize therapeutic drug monitoring in children (Anliker-Ort et al., 2024).

  • Spectrophotometric determination of phenol impurity in phenoxyethanol and phenol index of drinking water and municipal wastewater effluent after salting-out assisted liquid phase microextraction (SA-LPME).: This study offers a spectrophotometric method for detecting phenol impurities, enhancing water quality monitoring techniques (Roustaei et al., 2024).

  • A novel hybrid sensor array based on the polyphenol oxidase and its nanozymes combined with the machine learning based dual output model to identify tea polyphenols and Chinese teas.: This research introduces a hybrid sensor array employing polyphenol oxidase and its nanozymes for detecting tea polyphenols, showcasing the integration of enzymatic methods with machine learning for enhanced specificity and sensitivity in food analysis (Yang et al., 2024).

Other Notes

4-Aminoantipyrine has been used as a corrosion inhibitor of mild steel in 2 M HCl solution using different techniques: electrochemical impedance spectroscopy (EIS), potentiodynamic polarization and weight loss.
Reagent for the determination of H2O2

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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4-Aminoantipyrine as an inhibitor of mild steel corrosion in HCl solution
El-Rehim, SS Abd, Magdy AM Ibrahim, and K. F. Khaled
J. Appl. Electrochem., 29 (5), 593-599 (1999)
Michael Crone et al.
Wellcome open research, 6, 268-268 (2021-11-20)
Background: Diagnostic laboratories are currently required to provide routine testing of asymptomatic staff and patients as a part of their clinical screening for SARS-CoV-2 infection. However, these cohorts display very different disease prevalence from symptomatic individuals and testing capacity for
Y Saito et al.
Talanta, 34(7), 667-669 (1987-07-01)
Amberlite IRA 900 anion-exchange resin modified with manganese-tetrakis(sulphophenyl)-porphine has been used as a catalyst instead of peroxidase for the determination of hydrogen peroxide by the reaction 2H(2)O(2) + N,N-diethylaniline + 4-aminoantipyrine (catalyst)--> quinonoid dye (lambda(max) 550 nm) + 4H(2)O. The
Alireza Radmanesh et al.
Radiology, 297(1), E223-E227 (2020-05-22)
Diffuse leukoencephalopathy and juxtacortical and/or callosal microhemorrhages were brain imaging features in critically ill patients with coronavirus disease 2019. Coronavirus disease 2019 (COVID-19) has been reported in association with a variety of brain imaging findings such as ischemic infarct, hemorrhage
Biphasic Variation Over Time in Presenting Features of Patients With COVID-19.
Nazreen Jamal et al.
Pediatrics, 146(5) (2020-09-05)

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