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114537

Sigma-Aldrich

Phenol Red sodium salt

ACS reagent, Dye content 90 %

Synonym(s):

Phenolsulfonephthalein sodium salt

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About This Item

Empirical Formula (Hill Notation):
C19H13NaO5S
CAS Number:
34487-61-1
Molecular Weight:
376.36
Beilstein/REAXYS Number:
6260026
EC Number:
252-057-8
MDL number:
MFCD00066901
UNSPSC Code:
12171500
PubChem Substance ID:
24847180
NACRES:
NA.47

grade

ACS reagent

Quality Level

200

form

powder or crystals

composition

Dye content, 90%

clarity of soln

passes test

technique(s)

titration: suitable

color

red to very dark red

visual transition interval

6.8-8.2, yellow to red
6.8-8.2, yellow to red

mp

285 °C (dec.) (lit.)

λmax

423 nm

ε (extinction coefficient)

≥19000 at 422-426 nm in methanol
≥900 at 256-269 nm in methanol

storage temp.

room temp

SMILES string

[Na+].Oc1ccc(cc1)C2(OS(=O)(=O)c3ccccc23)c4ccc([O-])cc4

InChI

1S/C19H14O5S.Na/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19;/h1-12,20-21H;/q;+1/p-1

InChI key

HKHYOKBQJILTEI-UHFFFAOYSA-M

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Application

Phenol Red has been used for preparation of phosphate buffer saline (PBS)-with phenol red for microfluidic assay for simultaneous culture of multiple cell types. It has also been used for horseradish peroxidase-phenol red (HRP-PR) H2O2 (hydrogen peroxide) detection assay to identify redox cycling compounds.
Suitable for use as a pH indicator.

Biochem/physiol Actions

Phenol Red is a pH indicator which changes color from yellow to red.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H335

Hazard Classifications

Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels.
Shin Y, et al.
Nature Protocols, 7, 1247-1259 (2012)
Profiling the NIH Small Molecule Repository for compounds that generate H2O2 by redox cycling in reducing environments.
Soares KM, et al.
Assay and Drug Development Technologies, 8, 152-174 (2010)
TiO2 nanotube arrays of 1000 ?m length by anodization of titanium foil: phenol red diffusion.
Paulose M, et al.
The Journal of Physical Chemistry C, 111, 14992-14997 (2007)

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