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32142

Supelco

Pirbuterol acetate

VETRANAL®, analytical standard

Synonym(s):

(RS)-2-(tert-Butylamino)-1-(6-hydroxymethyl-5-hydroxy-2-pyridyl)ethanol acetate salt, 6-(2-tert-Butylamino-1-hydroxyethyl)-2-hydroxymethylpyridin-3-ol acetate

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About This Item

Empirical Formula (Hill Notation):
C12H20N2O3 · C2H4O2
CAS Number:
65652-44-0
Molecular Weight:
300.35
Beilstein/REAXYS Number:
13318829
EC Number:
265-862-4
MDL number:
MFCD07773091
UNSPSC Code:
41116107
PubChem Substance ID:
329754063
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

InChI

1S/C12H20N2O3.C2H4O2/c1-12(2,3)13-6-11(17)8-4-5-10(16)9(7-15)14-8;1-2(3)4/h4-5,11,13,15-17H,6-7H2,1-3H3;1H3,(H,3,4)

InChI key

QSXMZJGGEWYVCN-UHFFFAOYSA-N

Gene Information

human ... ADRB2(154)

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Application

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH8808
BCBW8968
BCBS4084V
SZBF006XV
SZBD102XV

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N E Robinson et al.
Equine veterinary journal, 32(5), 393-400 (2000-10-19)
During a trial to determine the dose response to the beta2-adrenergic agonist pirbuterol, we judged the severity of airway obstruction by use of a clinical scoring system and compared this to objective data obtained by quantitative measures of lung function.
P C Langley
Clinical therapeutics, 21(1), 236-253 (1999-03-25)
This paper reviews the impact of the use of technologically dissimilar beta-agonist aerosols--the Maxair Autohaler (pirbuterol acetate) breath-actuated aerosol and the traditional albuterol press-and-breathe inhaler-on the treatment costs of asthma. If, as clinical evidence would suggest, the breath-actuated aerosol is
E A Bronsky et al.
The Journal of asthma : official journal of the Association for the Care of Asthma, 30(6), 439-443 (1993-01-01)
The preferred form of acute bronchodilator therapy is to administer aerosolized beta-agonist by a metered-dose inhaler. Many patients cannot use this device efficiently, the major problem being coordination of dose release with inspiration. A new breath-actuated inhaler (the Autohaler actuator)
Management of chronic obstructive pulmonary disease.
T C Chinet
The New England journal of medicine, 329(13), 967-968 (1993-09-23)
F J Derksen et al.
Equine veterinary journal, 28(4), 306-310 (1996-07-01)
Aerosol administration of bronchodilators to horses is recommended for treatment of certain airway diseases such as 'heaves'. We have developed a novel, hand-held, metered-dose inhaler and we sought to determine the bronchodilator efficacy of the beta 2 adrenoceptor agonist pirbuterol
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