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Olaquindox

VETRANAL®, analytical standard

Synonym(s):

N-(2-Hydroxyethyl)-3-methyl-2-quinoxalinecarboxamide 1,4-dioxide

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About This Item

Empirical Formula (Hill Notation):
C12H13N3O4
CAS Number:
23696-28-8
Molecular Weight:
263.25
EC Number:
245-832-7
MDL number:
MFCD00210341
UNSPSC Code:
41116107
PubChem Substance ID:
329754726
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cc1c(C(=O)NCCO)[n+]([O-])c2ccccc2[n+]1[O-]

InChI

1S/C12H13N3O4/c1-8-11(12(17)13-6-7-16)15(19)10-5-3-2-4-9(10)14(8)18/h2-5,16H,6-7H2,1H3,(H,13,17)

InChI key

TURHTASYUMWZCC-UHFFFAOYSA-N

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General description

Olaquindox is an antibiotic veterinary drug, used as a growth promoter for pig farming.

Application

Olaquindox may be used as a reference standard in the determination of olaquindox in feed samples using matrix solid-phase dispersion extraction (MSPDE) and hydrophilic interaction ultra-high-pressure liquid chromatography (HILIC-UHPLC) with photodiode array detector.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

hcodes

H302,H334

Hazard Classifications

Acute Tox. 4 Oral - Resp. Sens. 1

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH1618
BCBW1743
SZBD099XV
SZBA074XV
8266X

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Jiajie Zou et al.
Mutation research, 676(1-2), 27-33 (2009-06-03)
Olaquindox, a synthetic antimicrobial compound, is widely used in China as feed additive for growth promotion. However, it is a mutagen with its functional mechanism yet to be unclear. The purpose of this study was to investigate the genotoxic effects
Chunmei Song et al.
Journal of agricultural and food chemistry, 59(17), 9319-9326 (2011-08-13)
A rapid immunochromatographic lateral flow test strip of competitive format has been developed for the specific determination of olaquindox (OLA) residues in pig urine and muscle tissues. The sensitivity of the test strip was found to be 1.58 ± 0.27
Zhao-Ying Liu et al.
Toxicology letters, 195(1), 51-59 (2010-03-12)
Olaquindox, N-(2-hydroxyethyl)-3-methyl-2-quinoxalinecarboxamide-1,4-di-N-oxide, is one of the quinoxaline-dioxides used widely as an antimicrobial growth promoter in pig production. Its toxicities were reported to be closely related to the formation of N-oxide reductive metabolites. The present study presents the metabolism and N-oxide
Plasmid-encoded multidrug efflux pump conferring resistance to olaquindox in Escherichia coli
Hansen HL, et al.
Antimicrobial Agents and Chemotherapy, 48(9), 3332-3337 (2004)
Biodegradability of metronidazole, olaquindox, and tylosin and formation of tylosin degradation products in aerobic soil--manure slurries
Ingerslev F and Halling-Sorensen B
Ecotoxicology and Environmental Safety, 48(3), 311-320 (2001)
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