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34198

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Ractopamine hydrochloride

VETRANAL®, analytical standard

Synonym(s):

4-{3-[2-Hydroxy-2-(4-hydroxyphenyl)ethyl]aminobutylphenol hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C18H23NO3 · HCl
CAS Number:
90274-24-1
Molecular Weight:
337.84
EC Number:
415-170-5
MDL number:
MFCD07781271
UNSPSC Code:
41116107
PubChem Substance ID:
329754886
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable
solid phase extraction (SPE): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

OC1=CC=C(C(O)CNC(C)CCC2=CC=C(O)C=C2)C=C1.Cl

InChI

1S/C18H23NO3.ClH/c1-13(2-3-14-4-8-16(20)9-5-14)19-12-18(22)15-6-10-17(21)11-7-15;/h4-11,13,18-22H,2-3,12H2,1H3;1H

InChI key

JHGSLSLUFMZUMK-UHFFFAOYSA-N

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General description

Ractopamine hydrochloride is a phenethanolamine β-adrenergic agonist (β-AA) that improves growth performance and affects carcass characteristics in livestock, through increased protein synthesis. Ractopamine hydrochloride is FDA approved animal feed additive used in some third countries like the USA, Canada, Japan, and Mexico for the growth promotion in fattening of pigs and cattle. In the USA, Ractopamine hydrochloride is authorized for use in pigs and cattle at a feed concentration of 5-20 mg kg-1 for finishing pigs and 10-30 mg kg-1 for cattle in confinement.

Application

The analytical standard can be used to:
  • Evaluate the comparative effects of ractopamine hydrochloride and zilpaterol hydrochloride on growth performance, carcass traits, and longissimus tenderness of finishing beef steers
  • Determine the effects of ractopamine hydrochloride on growth performance, carcass characteristics, physiological response to handling, and mobility during shipment for slaughter
  • Evaluate the effect of ractopamine hydrochloride on growth performance, carcass cutting yield, and processing characteristics of boneless hams and bellies from finishing pigs
  • Study the effects of ractopamine hydrochloride and zilpaterol hydrochloride on growth, diet digestibility, intake, and carcass characteristics of feedlot lambs
  • Evaluate the effects of ractopamine hydrochloride on growth performance, feed intake patterns, and acid-base balance in feedlot cattle

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG1332
BCBT4623
SZBC096XV
SZBA074XV
SZBA074X

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J A Hagenmaier et al.
Journal of animal science, 95(5), 1977-1992 (2017-07-21)
Feedlot cattle ( = 128; BW = 549 ± 60 kg) were used to evaluate the effects of ractopamine hydrochloride (RAC) on growth performance, physiological response to handling, and mobility during shipment for slaughter in a study utilizing a split-plot
Effect of ractopamine hydrochloride and zilpaterol hydrochloride on growth, diet digestibility, intake and carcass characteristics of feedlot lambs
Lopez-Carlos.A.M, et al.
Livestock Science, 131, 23-30 (2010)
Effect of ractopamine hydrochloride and zilpaterol hydrochloride on growth, diet digestibility, intake and carcass characteristics of feedlot lambs
Lopez-Carlos MA, et al.
Livestock Science, 23-30 null
S M Scramlin et al.
Journal of animal science, 88(5), 1823-1829 (2010-01-01)
Ractopamine hydrochloride (RAC) and zilpaterol hydrochloride (ZH) are beta-adrenergic agonists that improve growth performance and affect carcass characteristics. The objective of this study was to evaluate the comparative effects of RAC and ZH when fed to beef steers during the
Safety evaluation of ractopamine
European Food Safety Authority
EFSA Journal, 1041 null
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