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Ginsenoside Rg5

analytical standard

Synonym(s):

(3β, 12β,20E)-12-Hydroxydammara-20(22),24-dien-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

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About This Item

Empirical Formula (Hill Notation):
C42H70O12
CAS Number:
186763-78-0
Molecular Weight:
767.00
UNSPSC Code:
85151701
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥90.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

food and beverages

format

neat

storage temp.

2-8°C

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General description

Ginsenoside Rg5 is a diol-containing ginsenoside, that occurs naturally in Panax ginseng. It is found to be a promising agent in the treatment of Alzheimer′s disease.

Application

Ginsenoside Rg5 may be used as a reference standard in the determination of ginsenoside Rg5 in Korean red ginseng using high performance liquid chromatography coupled with evaporative light scattering detection (HPLC-ELSD).

Other Notes

This compound is commonly found in plants of the genus: panax

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Inhibitory effect of ginsenoside Rg5 and its metabolite ginsenoside Rh3 in an oxazolone-induced mouse chronic dermatitis model.
Shin W-Y, et al.
Archives of Pharmacal Research, 29(8), 685-690 (2006)
Ginsenoside-Rg5 suppresses cyclin E-dependent protein kinase activity via up-regulating p21Cip/WAF1 and down-regulating cyclin E in SK-HEP-1 cells.
K Y L, et al.
Anticancer Research, 17(2A), 1067-1072 (1997)
Ginsenoside Rg5 improves cognitive dysfunction and beta-amyloid deposition in STZ-induced memory impaired rats via attenuating neuroinflammatory responses.
Chu S, et al.
International Journal of Immunopharmacology, 19(2), 317-326 (2014)
Simultaneous quantification of 14 ginsenosides in Panax ginseng CA Meyer (Korean red ginseng) by HPLC-ELSD and its application to quality control.
Kim NS, et al.
Journal of Pharmaceutical and Biomedical Analysis, 45(1), 164-170 (2007)

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