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43348

Supelco

Farnesol

analytical standard, mixture of isomers, stabilized

Synonym(s):

3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol

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About This Item

Linear Formula:
(CH3)2C=CHCH2CH2C(CH3)=CHCH2CH2C(CH3)=CHCH2OH
CAS Number:
Molecular Weight:
222.37
Beilstein/REAXYS Number:
1763926
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥95.0% (GC)

shelf life

limited shelf life, expiry date on the label

contains

α-tocopherol (synthetic stabilizer)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.488-1.492
n20/D 1.489 (lit.)

bp

149 °C/4 mmHg (lit.)

density

0.886 g/mL at 20 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

C/C(CC/C=C(C)/CCC=C(C)C)=C\CO

InChI

1S/C15H26O/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16/h7,9,11,16H,5-6,8,10,12H2,1-4H3/b14-9+,15-11+

InChI key

CRDAMVZIKSXKFV-YFVJMOTDSA-N

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General description

Farnesol is a sesquiterpenoid, acting as a quorum-sensing molecule that inhibits filamentation in Candida albicans. It can exhibit chemotherapeutic activity toward pancreatic and other cancers.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

204.8 °F - closed cup

flash_point_c

96.00 °C - closed cup

ppe

Eyeshields, Gloves


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Certificates of Analysis (COA)

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Effects of the isoprenoids perillyl alcohol and farnesol on apoptosis biomarkers in pancreatic cancer chemoprevention.
DYB, et al.
Anticancer Research, 22(10), 3127-3134 (2002)
Sensitization of Staphylococcus aureus and Escherichia coli to Antibiotics by the Sesquiterpenoids Nerolidol, Farnesol, Bisabolol, and Apritone.
Brehm-Stecher FB and Johnson AE
Antimicrobial Agents and Chemotherapy, 47(10), 3357?3360-3357?3360 (2003)
Inhibition of Candida albicans Biofilm Formation by Farnesol, a Quorum-Sensing Molecule.
Ramage G, et al.
Applied and Environmental Microbiology, 68(11), 5459?5463-5459?5463 (2002)
Joung Hyuck Joo et al.
Cancer letters, 287(2), 123-135 (2009-06-13)
The isoprenoid alcohol farnesol is an effective inducer of cell cycle arrest and apoptosis in a variety of carcinoma cell types. In addition, farnesol has been reported to inhibit tumorigenesis in several animal models suggesting that it functions as a
A Lapczynski et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46 Suppl 11, S149-S156 (2008-07-22)
A toxicologic and dermatologic review of farnesol when used as a fragrance ingredient is presented.

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