436143
Sodium dodecyl sulfate
ACS reagent, ≥99.0%
Synonym(s):
Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
About This Item
grade
ACS reagent
Quality Level
description
anionic
62
assay
≥99.0%
form
solid
mol wt
288.38 g/mol
impurities
≤0.06 meq/g Titr. Base
≥96.0% fatty alcohols
<4.0% unsulfated alcohols
loss
≤1.0% loss on drying
mp
204-207 °C (lit.)
solubility
H2O: soluble 1 gm in 10 ml (opalescent solution)
cation traces
heavy metals (as Pb): ≤0.002%
λ
3 %H2O reference
UV absorption
λ: 220-350 nm Amax: ≤0.1
HLB
40
SMILES string
[Na+].CCCCCCCCCCCCOS([O-])(=O)=O
InChI
1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
InChI key
DBMJMQXJHONAFJ-UHFFFAOYSA-M
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General description
In protein biochemistry, SDS plays a pivotal role in protein extraction and SDS-PAGE (sodium dodecyl sulfate-polyacrylamide gel electrophoresis). Its ability to denature proteins by disrupting their secondary and tertiary structures allows for their uniform migration through a polyacrylamide gel matrix based on their molecular weight. This technique, SDS-PAGE, has become an indispensable tool for analyzing protein size and purity.
Beyond protein analysis, SDS also finds applications in nucleic acid extraction and hybridization techniques. Its detergent properties aid in the lysis of cells and the solubilization of cellular components, facilitating the extraction of DNA and RNA. This makes SDS a valuable reagent in various molecular biology protocols, including PCR (polymerase chain reaction) and Southern blotting. Sodium dodecyl sulfate stands as a versatile and widely used surfactant with a diverse range of applications due to its ability to solubilize, denature, and separate biological molecules for cell biology and biochemical research.
Application
Biochem/physiol Actions
Features and Benefits
- Highly versatile surfactant for your molecular biology and biochemical research
- Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
Other Notes
signalword
Danger
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
4.1B - Flammable solid hazardous materials
wgk_germany
WGK 2
flash_point_f
338.0 °F
flash_point_c
170 °C
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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