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Apigenin 7-glucoside

analytical standard

Synonym(s):

4′,5,7-Trihydroxyflavone 7-glucoside, Apigenin-7-O-glucoside, Apigetrin, Cosmosiin

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About This Item

Empirical Formula (Hill Notation):
C21H20O10
CAS Number:
578-74-5
Molecular Weight:
432.38
Beilstein/REAXYS Number:
65669
EC Number:
209-430-5
MDL number:
MFCD00016787
UNSPSC Code:
85151701
PubChem Substance ID:
329756537
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥97.0% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C=C(Oc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C21H20O10/c22-8-16-18(26)19(27)20(28)21(31-16)29-11-5-12(24)17-13(25)7-14(30-15(17)6-11)9-1-3-10(23)4-2-9/h1-7,16,18-24,26-28H,8H2/t16-,18-,19+,20-,21-/m1/s1

InChI key

KMOUJOKENFFTPU-QNDFHXLGSA-N

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General description

Apigenin 7-glucoside is a flavone belonging to the class of polyphenols and is commonly found in Thymus species. It shows a broad spectrum of pharmacological properties such as antispasmodic, bactericidal, expectorant, antihelmintic, adstringent, antitussive and carminative agent.

Application

Apigenin 7-glucoside may be used as an analytical reference standard for the quantification of the analyte in Thymus species and Olea europaea using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: achillea ginkgo humulus hypericum melissa mentha pimpinella plantago salvia silybum thymus

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number

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Luteolin 7-O-Glucoside United States Pharmacopeia (USP) Reference Standard

USP

1370837

Luteolin 7-O-Glucoside

Nepetin 7-glucoside phyproof® Reference Substance

PHL83306

Nepetin 7-glucoside

Apigenin ≥95.0% (HPLC)

Sigma-Aldrich

10798

Apigenin

Homoplantaginin ≥98% (HPLC)

Sigma-Aldrich

SML2157

Homoplantaginin

Apigenin 7-O-neohesperidoside ≥99.0% (HPLC)

Sigma-Aldrich

12676

Apigenin 7-O-neohesperidoside

Luteolin 7-glucoside primary reference standard

03600585

Luteolin 7-glucoside

Luteolin 7-O-β-D-glucoside ≥98.0% (HPLC)

Sigma-Aldrich

74284

Luteolin 7-O-β-D-glucoside

Luteolin ≥98% (TLC), powder

Sigma-Aldrich

L9283

Luteolin

Determination of polyphenolic compounds by liquid chromatography-mass spectrometry in Thymus species
Boros B, et al.
Journal of Chromatography A, 1217(51), 7972-7980 (2010)
Janmejai K Srivastava et al.
Journal of agricultural and food chemistry, 55(23), 9470-9478 (2007-10-18)
Chamomile (Matricaria chamomilla), a popular herb valued for centuries as a traditional medicine, has been used to treat various human ailments; however, its anticancer activity is unknown. We evaluated the anticancer properties of aqueous and methanolic extracts of chamomile against
Eri Nakazaki et al.
European journal of nutrition, 52(1), 25-35 (2011-11-25)
Nutritional factors is one of the most important regulators in the progression of cancer. Some dietary elements promote the growth of cancer but others, such as plant-derived compounds, may reverse this process. We tried to investigate yet another approach of
Rapid high-performance liquid chromatography analysis for the quantitative determination of oleuropein in Olea europaea leaves
Savournin C, et al.
Journal of Agricultural and Food Chemistry, 49(2), 618-621 (2001)
Laura Hanske et al.
The Journal of nutrition, 139(6), 1095-1102 (2009-05-01)
We investigated the impact of human intestinal microbiota on bioavailability of the flavone apigenin-7-glucoside (A7G) by comparing germ-free and human microbiota-associated (HMA) rats. First, the ability of the human intestinal microbiota to convert A7G was proven in vitro by incubating
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