60765
Silica gel
high-purity grade, with ~15% calcium sulfate and fluorescent indicator, GF254, suitable for thin layer chromatography (TLC)
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About This Item
CAS Number:
EC Number:
MDL number:
UNSPSC Code:
41115711
PubChem Substance ID:
NACRES:
NC.07
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grade
high-purity grade
Quality Level
form
powder
quality
with ~15% calcium sulfate and fluorescent indicator
manufacturer/tradename
Sigma-Aldrich
technique(s)
thin layer chromatography (TLC): suitable
surface area
500 m2/g
particle size
<20 μm
>632 mesh
pore size
0.8 cm3/g pore volume
60 Å pore size
bp
2230 °C
mp
>1600 °C
SMILES string
O=[Si]=O
InChI
1S/O2Si/c1-3-2
InChI key
VYPSYNLAJGMNEJ-UHFFFAOYSA-N
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General description
Silica gel is a rigid 3D network of colloidal silica. It is exclusively used as a support material for the active titanium(III) centers in Ziegler-Natta catalysts. Silica gel allows a controlled fragmentation resulting in the formation of uniform polymer particles with narrow particle size distribution and high bulk density. Silica gel is classified as below:
a. Aquagel - pores are filled with water
b. Xerogel - by the process of evaporation, aqueous phase in the pores are removed
c. Aerogel - solvent is removed by supercritical extraction
a. Aquagel - pores are filled with water
b. Xerogel - by the process of evaporation, aqueous phase in the pores are removed
c. Aerogel - solvent is removed by supercritical extraction
Application
- Chromatographic Separation: Silica gel is widely used as a stationary phase in chromatography for the separation of various chemical compounds. Innovations in silica gel modification, such as pentabromobenzyl group-modified silica gel, have enhanced the separation efficiency for metabolites like nicotinamide. This application is critical for pharmaceutical analysis and metabolomics studies, providing high precision and accuracy in the quantification of biologically relevant molecules (Ozaki et al., Analytical Biochemistry, 2022).
- Environmental Pollutant Detection: Silica gel is used to create molecularly imprinted polymers (MIPs) that selectively recognize and bind environmental pollutants. A notable application involves the embedding of quantum dots in molecularly imprinted silica gel to detect aminoimidazo-azaarenes (AIAs) in food samples. This method offers high selectivity and sensitivity, making it a powerful tool for food safety and environmental monitoring (Qiao et al., Current Analytical Chemistry, 2021).
wgk_germany
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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