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Supelco

1-Methoxy-2-propanol

analytical standard

Synonym(s):

Propylene glycol methyl ether, Propyleneglycol monomethyl ether

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About This Item

Linear Formula:
CH3CH(OH)CH2OCH3
CAS Number:
107-98-2
Molecular Weight:
90.12
Beilstein/REAXYS Number:
1731270
EC Number:
203-539-1
MDL number:
MFCD00004537
UNSPSC Code:
41116107
PubChem Substance ID:
329760094
NACRES:
NA.24

grade

analytical standard

Quality Level

100

vapor density

3.12 (vs air)

vapor pressure

10.9 mmHg ( 25 °C)

assay

≥99.7% (GC)

autoignition temp.

532 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

13.8 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.403 (lit.)
n20/D 1.403

bp

118-119 °C (lit.)

density

0.916 g/mL at 25 °C (lit.)

application(s)

environmental

format

neat

SMILES string

CC(O)COC

InChI

1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3

InChI key

ARXJGSRGQADJSQ-UHFFFAOYSA-N

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General description

1-Methoxy-2-propanol is one of the most common propylene-based glycol ethers that find potential use in several industrial and commercial applications, major use being as a component of paints, varnishes, inks, etc. It is often utilized as a less potent substitute for short-chained ethylene glycol ethers.

Application

1-Methoxy-2-propanol may be used as an analytical standard for the determination of the analyte in human and animal biological samples by various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

hcodes

H226,H336

Hazard Classifications

Flam. Liq. 3 - STOT SE 3

target_organs

Central nervous system

wgk_germany

WGK 1

flash_point_f

closed cup

flash_point_c

closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
BCCD8085
BCBX4461
BCBR2420V
BCBL3411V
1413553V

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Gas-chromatographic determination of propylene-and diethylene glycol ethers in urine
Hubner B, et al.
Fresenius Journal of Analytical Chemistry, 342(9), 746-748 (1992)
J Laitinen et al.
Journal of chromatography. B, Biomedical sciences and applications, 694(1), 93-98 (1997-06-20)
At the end of a workweek 23 silkscreen printers gave a urine sample for capillary gas chromatographic analysis for 1,2-propanediol. The mean concentration was 2.52 (S.D. 2.01) mmol mol creatinine(-1) (median=1.76, n=23). The urinary excretion of 1,2-propanediol was linearly dependent
J Y Domoradzki et al.
Toxicological sciences : an official journal of the Society of Toxicology, 75(1), 31-39 (2003-07-15)
The kinetic equivalency of propylene glycol monomethyl ether (PGME), derived from propylene glycol monomethyl ether acetate (PGMEA), as well as the parent compound (PGME) following intravenous administration to Fischer 344 rats was evaluated. In addition, in vitro hydrolysis rates of
Nancy B Hopf et al.
Toxicology letters, 211(1), 77-84 (2012-03-17)
Aging adults represent the fastest growing population segment in many countries. Physiological and metabolic changes in the aging process may alter how aging adults biologically respond to pollutants. In a controlled human toxicokinetic study (exposure chamber; 12 m³), aging volunteers
H H Emmen et al.
Toxicology letters, 140-141, 249-259 (2003-04-05)
The objective of this study was to establish the possible occurrence of eye irritation and subjective symptoms in human volunteers exposed to propylene glycol monomethyl ether (PGME) vapour at concentrations of 0, 100 and 150 ppm. Testing was conducted in
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