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80821

Supelco

(2S)-2-(5-Iodo-6-methoxynaphthalen-2-yl)propanoic acid

pharmaceutical impurity standard

Synonym(s):

Naproxen Impurity D (PhEur), (αS)-5-Iodo-6-methoxy-α-methyl-2-naphthaleneacetic acid, (2S)-2-(5-Iodo-6-methoxy-2-naphthyl)propionic acid, (S)-5-Iodo naproxen, Naproxen EP Impurity D

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About This Item

Empirical Formula (Hill Notation):
C14H13IO3
CAS Number:
Molecular Weight:
356.16
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.24

Quality Level

API family

naproxen

assay

≥98.0% (HPLC)

optical activity

[α]/D 41±4°, c = 1 in chloroform

shelf life

limited shelf life, expiry date on the label

impurities

≤0.5% water

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

C[C@H](C(O)=O)C1=CC2=CC=C(OC)C(I)=C2C=C1

InChI

1S/C14H13IO3/c1-8(14(16)17)9-3-5-11-10(7-9)4-6-12(18-2)13(11)15/h3-8H,1-2H3,(H,16,17)/t8-/m0/s1

InChI key

MNTGUQDQTXNYMT-QMMMGPOBSA-N

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Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_c

Not applicable


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Ina N Eckert et al.
Frontiers in immunology, 11, 616531-616531 (2021-02-16)
Myeloid-derived suppressor cells (MDSCs) represent a major population controlling T cell immune responses. However, little is known about their molecular requirements for homing and T cell interaction to mediate suppression. Here, we investigated the functional role of the homing and
Alex Kiepas et al.
Journal of cell science, 133(4) (2020-01-29)
Fluorescence illumination can cause phototoxicity that negatively affects living samples. This study demonstrates that much of the phototoxicity and photobleaching experienced with live-cell fluorescence imaging occurs as a result of 'illumination overhead' (IO). This occurs when a sample is illuminated

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