901990
Tetrazine-acid
Synonym(s):
4-(1,2,4,5-Tetrazin-3-yl)benzeneacetic acid
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About This Item
Empirical Formula (Hill Notation):
C10H8N4O2
CAS Number:
Molecular Weight:
216.20
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.22
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form
powder or crystals
availability
available only in USA
storage temp.
−20°C
Application
Tetrazine-acid demonstrates exceptionally fast cycloaddition kinetics with trans-cyclooctene (TCO) as the dienophile (up to 30,000 M-1 s-1). These have been the fastest kinetics reported for a bio orthogonal reaction. The chemical stability of tetrazines is substantially lower compared to methyltetrazines, thus requiring more careful selection of reagents and conditions for chemical transformation. However, tetrazine chemistry is still in an acceptable range for many applications.
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Danger
hcodes
Hazard Classifications
Self-react. C
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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