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90323

Supelco

Clofibric acid

analytical standard

Synonym(s):

2-(p-Chlorophenoxy)-2-methylpropionic acid, α-(p-Chlorophenoxy)isobutyric acid, Clofibric acid

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About This Item

Linear Formula:
ClC6H4OC(CH3)2CO2H
CAS Number:
882-09-7
Molecular Weight:
214.65
EC Number:
212-925-9
MDL number:
MFCD00004192
UNSPSC Code:
77101502
PubChem Substance ID:
329769900
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥99.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤0.5% water

mp

120-122 °C (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CC(C)(Oc1ccc(Cl)cc1)C(O)=O

InChI

1S/C10H11ClO3/c1-10(2,9(12)13)14-8-5-3-7(11)4-6-8/h3-6H,1-2H3,(H,12,13)

InChI key

TXCGAZHTZHNUAI-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCD0182
BCBX5470
BCBQ9630V
BCBK9475V
BCBK9475

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Agustina Manassero et al.
Environmental science and pollution research international, 22(2), 926-937 (2014-03-14)
A kinetic study of the photocatalytic degradation of the pharmaceutical clofibric acid is presented. Experiments were carried out under UV radiation employing titanium dioxide in water suspension. The main reaction intermediates were identified and quantified. Intrinsic expressions to represent the
Da-Bing Ren et al.
Journal of chromatography. A, 1355, 80-85 (2014-06-22)
Selection of an appropriate solvent system is of great importance for a successful counter-current chromatography separation. In this work, the nonrandom two-liquid (NRTL) model, a thermodynamic method, was used for predicting the partition coefficient based on a few measured partition
Zein Shaban Ibrahim et al.
Bioscience, biotechnology, and biochemistry, 78(9), 1550-1559 (2014-07-24)
Peroxisome proliferator activated receptor α (PPARα) ligands, fibrates used to control hyperlipidemia. We demonstrated CYP2B induction by clofibric acid (CFA) however, the mechanism was not clear. In this study, HepG2 cells transfected with expression plasmid of mouse constitutive androstane receptor
Martin J A Schackmann et al.
Biochimica et biophysica acta, 1851(2), 231-237 (2014-12-17)
X-linked adrenoleukodystrophy (X-ALD) is a neurometabolic disease that is caused by mutations in the ABCD1 gene. ABCD1 protein deficiency impairs peroxisomal very long-chain fatty acid (VLCFA) degradation resulting in increased cytosolic VLCFA-CoA levels, which are further elongated by the VLCFA-specific
Julia Martín et al.
The Science of the total environment, 503-504, 97-104 (2014-06-10)
Sewage sludge disposal onto lands has been stabilized previously but still many pollutants are not efficiently removed. Special interest has been focused on pharmaceutical compounds due to their potential ecotoxicological effects. Nowadays, there is scarce information about their occurrence in
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