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N-(n-Butyl)thiophosphoric triamide

analytical standard

Synonym(s):

N-Butylphosphorothioic triamide, N-Butylthiophosphoric triamide

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About This Item

Empirical Formula (Hill Notation):
C4H14N3PS
CAS Number:
94317-64-3
Molecular Weight:
167.21
MDL number:
MFCD00269941
UNSPSC Code:
12352103
PubChem Substance ID:
329770057
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

impurities

≤1.0% water (calculated from elemental analysis)

mp

56-58 °C (lit.)

format

neat

storage temp.

2-8°C

SMILES string

S=P(NCCCC)(N)N

InChI

1S/C4H14N3PS/c1-2-3-4-7-8(5,6)9/h2-4H2,1H3,(H5,5,6,7,9)

InChI key

HEPPIYNOUFWEPP-UHFFFAOYSA-N

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General description

N-(n-Butyl)thiophosphoric triamide (nBPTT), an active ingredient in nitrogen stabilizers, is widely used as a urease inhibitor. Its mode of action involves the inhibition of urease enzyme thereby improving the efficiency of urea-containing fertilizers. nBPTT is also effective in increasing plant yields and reducing ammonia losses when employed with surface-applied urea and urea ammonium nitrate solutions.

Application

N-(n-Butyl)thiophosphoric triamide may be used as an analytical reference standard for the quantification of the analyte in soil samples, bovine milk and tissue extracts using chromatography techniques.

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pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Repr. 2

wgk_germany

WGK 1

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HPLC Method for the Analysis of the Urease Inhibitor N-(n-butyl) thiophosphoric Triamide and Its Metabolites
Douglass AE and Hendrickson LL
Journal of Agricultural and Food Chemistry, 39(12), 2318-2321 (1991)
Lindsay M LaFave et al.
Cancer cell, 38(2), 212-228 (2020-07-25)
Regulatory networks that maintain functional, differentiated cell states are often dysregulated in tumor development. Here, we use single-cell epigenomics to profile chromatin state transitions in a mouse model of lung adenocarcinoma (LUAD). We identify an epigenomic continuum representing loss of

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