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93893

Supelco

Physcion

analytical standard

Synonym(s):

1,8-Dihydroxy-3-methoxy-6-methylanthraquinone, 6-O-Methylemodin, 6-Methoxychrysophanic acid, Emodin-3-methyl ether, Parietin, Rheochrysidin

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About This Item

Empirical Formula (Hill Notation):
C16H12O5
CAS Number:
521-61-9
Molecular Weight:
284.26
Beilstein/REAXYS Number:
6770499
EC Number:
208-315-7
MDL number:
MFCD00017374
UNSPSC Code:
85151701
PubChem Substance ID:
329770284
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1

InChI

1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3

InChI key

FFWOKTFYGVYKIR-UHFFFAOYSA-N

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General description

Physcion is an anthraquinone derivative and is available as the active constituent of Chinese medicinal plants such as Rhubarb, Polygonum cuspidatum and Reynoutria multiflora. It exhibits various biological activities such as antitumor, antimicrobial, antifungal, antioxidant and antihuman cytomegalovirus activity.

Application

Physcion may be used as an analytical reference standard for the quantification of the analyte in medicinal plants, pharmaceutical preparations, vegetables, herbs and liquors using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Anthraquinone-derivative found in medicinal herbs.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

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Sigma-Aldrich

A7687

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Sigma-Aldrich

275611

Rhein

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Sigma-Aldrich

R7269

Rhein

Occurrence of emodin, chrysophanol and physcion in vegetables, herbs and liquors. Genotoxicity and anti-genotoxicity of the anthraquinones and of the whole plants
Mueller O.S, et al.
Food And Chemical Toxicology, 37(5), 481-491 (1999)
Henning Hopf et al.
Acta crystallographica. Section C, Crystal structure communications, 68(Pt 8), o317-o319 (2012-08-02)
The structure of the title compound, 7-methoxy-2-methyl-4,5-dihydroxyanthracene-9,10-dione, C(16)H(12)O(5), was originally reported by Ulický et al. [Acta Cryst. (1991). C47, 1879-1881] in the space group P2(1)2(1)2(1) [polymorph (Io)]. The new polymorph, (Im), crystallizes in the space group P2(1)/c. The molecular structures
Gizachew Alemayehu et al.
Natural product communications, 5(5), 747-750 (2010-06-05)
Chrysophanol, physcion, emodin, floribundone-1, 5,7'-physcion-fallacinol, and the novel 5,7'-physcion-physcion-10'-C-alpha-arabinopyranoside were isolated from the stem bark of Senna septemtrionalis. The structures of these secondary metabolites were determined on the basis of spectroscopic analysis, especially from NMR spectra in conjunction with COSY
Y-R Kwon et al.
Oral diseases, 16(2), 204-209 (2010-04-09)
The aim of this study was to separate the anti-acidogenic substances against Streptococcus mutans UA 159 from Polygonum cuspidatum. The anti-acidogenic substances were separated by a series of liquid-liquid fractionations followed by normal-phase silica gel liquid chromatography, based on high-performance
Jie Yu et al.
Journal of ethnopharmacology, 137(3), 1291-1299 (2011-08-16)
Radix Polygoni Multiflori (RPM) and Radix Polygoni Multiflori Praeparata (RPMP) were traditionally widely used as Chinese herbal medicine. However, liver adverse reactions caused by RPM or RPMP were frequently reported all around the world recent years. The aim of this
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