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M0120000

Malathion

European Pharmacopoeia (EP) Reference Standard

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About This Item

Empirical Formula (Hill Notation):
C10H19O6PS2
CAS Number:
121-75-5
Molecular Weight:
330.36
Beilstein/REAXYS Number:
1804525
MDL number:
MFCD00036233
UNSPSC Code:
41116107
PubChem Substance ID:
329817727
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

malathion

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

shipped in

wet ice

storage temp.

−20°C

SMILES string

CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC

InChI

1S/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3

InChI key

JXSJBGJIGXNWCI-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Malathion EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Shereene Idriss et al.
Journal of drugs in dermatology : JDD, 8(8), 715-720 (2009-08-12)
Malathion is an under-recognized and under-utilized therapy for head lice and scabies largely due to misperceptions about its safety profile. Specifically, its pure form as it exists in pharmaceutical preparations is non-toxic to humans in the low doses available. While
Droplet size characterization of three aerial malathion spray programs.
T Younglove et al.
Bulletin of environmental contamination and toxicology, 53(4), 493-500 (1994-10-01)
P Flessel et al.
Environmental and molecular mutagenesis, 22(1), 7-17 (1993-01-01)
Mammalian in vivo and in vitro studies of technical or commercial grade malathion and its metabolite malaoxon show a pattern of induction of chromosome damage, as measured by chromosome aberrations, sister chromatid exchanges, and micronuclei. Experiments with purified (> 99%)
D L Sudakin et al.
Journal of toxicology. Clinical toxicology, 38(1), 47-50 (2000-03-04)
A 33-year-old female ingested an unknown quantity of malathion in a suicide attempt. Cholinergic signs consistent with severe organ, phosphate intoxication developed and were treated within 6 hours of ingestion. Intravenous atropine and a continuous infusion of pralidoxime (400 mg/h)
Y Prathibha et al.
Ecotoxicology and environmental safety, 102, 210-219 (2014-01-29)
Pesticides like malathion have the potential to disrupt development and reproduction of aquatic organisms including fishes. To investigate the likely consequences of malathion exposure at low doses in juvenile catfish, Clarias batrachus, we studied the expression pattern of genes encoding
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