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M0430

Sigma-Aldrich

Methyl cellulose

26.0-33.0% (methoxyl group, on Dry Basis), meets USP testing specifications, viscosity: 400 cP

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About This Item

CAS Number:
9004-67-5
MDL number:
MFCD00081763
UNSPSC Code:
12352201
PubChem Substance ID:
24896553
NACRES:
NA.21

agency

USP/NF
meets USP testing specifications

Quality Level

200

assay

26.0-33.0% (methoxyl group, on Dry Basis)

form

powder

useful pH range

5.0-8.0 (2% in water)

viscosity

320-480 cP, 2 % in water(20 °C)

application(s)

pharmaceutical (small molecule)

SMILES string

[*]OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO[*])O[C@@H](O[*])[C@H](O[*])[C@H]2O[*])[C@H](O[*])[C@@H](O[*])[C@@H]1O[*]

InChI key

YLGXILFCIXHCMC-JHGZEJCSSA-N

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General description

Methyl cellulose is an odorless and tasteless material. It is tough and non-toxic. Due to these properties, methyl cellulose is used as an adhesive in the food packaging industry. In water-soluble adhesives, it is utilized as a thickening agent.

Application

Methyl cellulose has been used as a supplement of Mammacult media for mammosphere culture from SUM159 TN breast cancer cells. It has also been used to formulate drugs such as ITI-007 and PCC0104005 to characterize their functional activity.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Functional profile of a novel modulator of serotonin, dopamine, and glutamate neurotransmission
Snyder GL, et al.
Psychopharmacology, 232(3), 605-621 (2015)
In Vitro and In Vivo Characterization of PCC0104005, a Novel Modulator of Serotonin-Dopamine Activity, as an Atypical Antipsychotic Drug
Xu Y,et al.
Scientific Reports, 8(1), 6892-6892 (2018)
Yanan Xu et al.
Scientific reports, 8(1), 6892-6892 (2018-05-04)
PCC0104005 is a novel drug candidate for treating schizophrenia that displays high affinity for serotonin, dopamine, and noradrenaline receptors, including partial agonism at dopamine D2, D3, D4, serotonin 5-HT1A, and 5-HT2A receptors and antagonism at 5-HT2B, 5-HT6, and 5-HT7 receptors.
Handbook of Adhesives and Surface Preparation (2011)
Nuclear basic fibroblast growth factor regulates triple-negative breast cancer chemo-resistance
Li S, et al.
Breast Cancer Research, 17(1), 91-91 (2015)
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