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M1755220

Methylprednisolone hydrogen succinate for performance test

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Methylprednisolone hemisuccinate, 11β,17,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-succinate, Methylprednisolone hydrogen succinate

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About This Item

Empirical Formula (Hill Notation):
C26H34O8
CAS Number:
2921-57-5
Molecular Weight:
474.54
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

methylprednisolone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/q;+1/p-1/t14-,16-,17-,19-,23+,24-,25-,26-;/m0./s1

InChI key

FQISKWAFAHGMGT-SGJOWKDISA-M

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Methylprednisolone hydrogen succinate for performance test EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Methylprednisolone hemisuccinate, United States Pharmacopeia (USP) Reference Standard

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M1755200

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Methylprednisolone, Pharmaceutical Secondary Standard; Certified Reference Material

Y0001759

Methylprednisolone hydrogen succinate for peak identification, European Pharmacopoeia (EP) Reference Standard

Y0001736

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Y0001760

Methylprednisolone acetate for system suitability, European Pharmacopoeia (EP) Reference Standard

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Methylprednisolone for system suitability A, European Pharmacopoeia (EP) Reference Standard

1435036

Methylprednisolone Related Compound C, United States Pharmacopeia (USP) Reference Standard

1435014

Methylprednisolone Related Compound A, United States Pharmacopeia (USP) Reference Standard

BP248

Methylprednisolone, British Pharmacopoeia (BP) Reference Standard

BP249

Methylprednisolone acetate, British Pharmacopoeia (BP) Reference Standard

BP572

Deltamedrane, British Pharmacopoeia (BP) Reference Standard

1437042

Methyl Prednisolone Hemisuccinate Related Compound D, United States Pharmacopeia (USP) Reference Standard

1437020

Methylprednisolone Hemisuccinate Related Compound B, United States Pharmacopeia (USP) Reference Standard

PHR3043

Methylprednisolone Related Compound C, pharmaceutical secondary standard, certified reference material

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Repr. 1B - STOT RE 2

target_organs

Adrenal gland,Immune system

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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S Pescina et al.
International journal of pharmaceutics, 451(1-2), 12-17 (2013-05-01)
Trans-scleral iontophoresis, i.e. the application of small electric current to enhance drug transport across sclera is an option for non-invasive delivery of corticosteroids to the posterior segment of the eye. In this paper, in vitro trans-scleral iontophoresis of methylprednisolone hemisuccinate
Hirofumi Oyama et al.
Neurologia medico-chirurgica, 52(10), 769-773 (2012-10-26)
A 51-year-old female with a history of rheumatoid arthritis rapidly developed anterior neck pain and paresis in the left upper and lower extremities and right lower extremity, sensory disturbance in the left upper and lower extremities, and bladder and rectal
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A patient with a Caspr2 autoantibodies-associated syndrome had an unusual clinical triad and an excellent response to B-cell-anergizing therapy using the humanized monoclonal antibody tocilizumab directed against the interleukin 6 (IL-6) receptor. A 55-year-old man had an atypical clinical triad
Long-term selective IgE-mediated hypersensitivity to hydrocortisone sodium succinate.
G F Calogiuri et al.
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Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 48(3), 407-410 (2013-05-07)
Although chemotherapy combined with G-CSF is an effective method for hematopoietic stem cell mobilization, standard chemotherapy protocol leading to best stem cell yield is not defined. In our study, we aimed to assess the impact of chemotherapy choice on mobilization
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