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P1472

Sigma-Aldrich

Potassium carbonate

meets USP testing specifications

Synonym(s):

Carbonic acid, Pearl ash, Salt of tartar, dipotassium salt, potash

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About This Item

Linear Formula:
K2CO3
CAS Number:
Molecular Weight:
138.21
Beilstein/REAXYS Number:
4267587
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

agency

USP/NF
meets USP testing specifications

Quality Level

assay

99.5-100.5%

form

crystalline

mp

891 °C (lit.)

solubility

soluble 138 g/L at 20 °C (completely)

application(s)

pharmaceutical (small molecule)

SMILES string

[K+].[K+].[O-]C([O-])=O

InChI

1S/CH2O3.2K/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2

InChI key

BWHMMNNQKKPAPP-UHFFFAOYSA-L

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General description

Potassium carbonate(K2CO3), also known as potash or pearl ash, is a white potassium salt. It is soluble in water to form a strong alkaline solution.

Application


  • Improved 2-pyridyl reductive homocoupling reaction using biorenewable solvent Cyrene(dihydrolevoglucosenone).: This study highlights the use of potassium carbonate as a base in a green chemistry context, demonstrating improved reductive homocoupling reactions with the use of the biorenewable solvent Cyrene. The findings suggest significant applications in sustainable chemical processes (Webb et al., 2023).

  • Synthesis, Characterization and Biological Evaluation of Magnolol and Honokiol Derivatives with 1,3,5-Triazine of Metformin Cyclization.: This research discusses the synthesis and biological evaluation of novel derivatives using potassium carbonate, which plays a crucial role in the cyclization process. The study has implications for drug development and medicinal chemistry (Ren et al., 2020).

  • Synthesis of (18)F-radiolabeled organophosphine fluorides for thiol-chemoselective peptide conjugation.: The use of potassium carbonate in the synthesis of radiolabeled compounds is detailed in this paper, highlighting its application in biochemistry and molecular biology for the development of novel imaging agents (Zhuang et al., 2020).

  • Synthesis of well-defined phosphate-methylated DNA fragments: the application of potassium carbonate in methanol as deprotecting reagent.: This study focuses on the critical role of potassium carbonate in the deprotection step during the synthesis of methylated DNA fragments, with implications for genetic research and biotechnology (Kuijpers et al., 1990).

Biochem/physiol Actions

Potassium carbonate(K2CO3) is used as a drying agent for ketones, alcohols, amines, and non-acidic compounds before distillation. It serves as a buffering agent and controls pH during wine and mead production. Potassium carbonate is also used in the extraction of artemisinin, a potent antimalarial drug, from Artemisia annua plant extracts.

Legal Information

CYRENE is a trademark of Circa Group Pvt Ltd

pictograms

Exclamation mark

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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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K Y Foo et al.
Bioresource technology, 104, 679-686 (2011-11-22)
This work explores the feasibility of orange peel, a citrus processing biomass as an alternative precursor for preparation of activated carbon (OPAC) via microwave assisted K(2)CO(3) activation. The operational parameters, chemical impregnation ratio, microwave power and irradiation time on the
Carlos Arroniz et al.
Organic letters, 15(4), 910-913 (2013-02-05)
ortho-Arylation of ortho-substituted benzoic acids is a challenging process due to the tendency of the reaction products toward Pd-catalyzed protodecarboxylation. A simple method for preventing decarboxylation in sterically hindered benzoic acids is reported. The method described represents a reliable and
K Y Foo et al.
Bioresource technology, 102(20), 9794-9799 (2011-08-31)
Sunflower seed oil residue, a by-product of sunflower seed oil refining, was utilized as a feedstock for preparation of activated carbon (SSHAC) via microwave induced K(2)CO(3) chemical activation. SSHAC was characterized by Fourier transform infrared spectroscopy, nitrogen adsorption-desorption and elemental
K Y Foo et al.
Bioresource technology, 111, 425-432 (2012-03-06)
Wood sawdust was converted into a high-quality activated carbon (WSAC) via microwave-induced K(2)CO(3) activation. The operational variables including chemical impregnation ratio, microwave power and irradiation time on the carbon yield and adsorption capability were identified. The surface physical characteristics of
Je-Lueng Shie et al.
Bioresource technology, 102(23), 11011-11017 (2011-10-07)
This study examined the effects of additives of potassium carbonate (K2CO3) and zinc oxide (ZnO) on the pyrolysis of waste sunflower-oil cake using a 60 kW pilot-scale plasma torch reactor. The major gaseous products were CO and H2. The productions

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