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PHL80822

Linarin

phyproof® Reference Substance

Synonym(s):

5,7-Dihydroxy 4′-methoxyflavone 7-rutinoside, 7-((6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl)oxy)-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one, Acacetin-7-rutinoside, Buddleoside, Linarigenin glycoside

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About This Item

Empirical Formula (Hill Notation):
C28H32O14
CAS Number:
Molecular Weight:
592.55
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

primary reference standard

product line

phyproof® Reference Substance

assay

≥90.0% (HPLC)

manufacturer/tradename

PhytoLab

application(s)

food and beverages

format

neat

InChI

1S/C28H32O14/c1-11-21(31)23(33)25(35)27(39-11)38-10-19-22(32)24(34)26(36)28(42-19)40-14-7-15(29)20-16(30)9-17(41-18(20)8-14)12-3-5-13(37-2)6-4-12/h3-9,11,19,21-29,31-36H,10H2,1-2H3/t11-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1

InChI key

YFVGIJBUXMQFOF-PJOVQGMDSA-N

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General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application


  • Linarin as a Neuroprotective Agent Studies: Linarin demonstrated potential neuroprotective effects, ameliorating ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress targeting AKR1B1, which suggests its applicability in the development of treatments for neurodegenerative disorders (Zhang et al., 2024).

  • Anti-inflammatory Effects of Linarin in Biochemistry: The anti-inflammatory properties of Linarin make it a significant compound for research in pharmacological sciences, as it might lead to new insights into the modulation of inflammatory pathways in chronic diseases (Cheriet et al., 2024).

  • Linarin in Chromatography and Spectrometry Analysis: As a chromatography standard, Linarin is essential for developing analytical methods that ensure the quality control of medicinal plants and herbal products, which is key for natural product research and drug development (Gontar et al., 2024).

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Soo-Il Kim et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 79, 153351-153351 (2020-09-29)
Since enhanced bone resorption due to osteoclast differentiation and activation cause skeletal diseases, there is a growing need in therapeutics for combating bone-resorbing osteoclasts. Botanical antioxidants are being increasingly investigated for their health-promoting effects on bone. Edible Cirsium setidens contains

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