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PHR1350

Supelco

Cytosine

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Cytosine, 4-Amino-2-hydroxypyrimidine, 4-Aminopyrimidin-2-(1H)-one

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About This Item

Empirical Formula (Hill Notation):
C4H5N3O
CAS Number:
71-30-7
Molecular Weight:
111.10
Beilstein/REAXYS Number:
2637
EC Number:
200-749-5
MDL number:
MFCD00006034
UNSPSC Code:
41116107
PubChem Substance ID:
329823334
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

agency

traceable to USP 1162148

API family

cytosine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

>300 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

NC1=NC(=O)NC=C1

InChI

1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)

InChI key

OPTASPLRGRRNAP-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Cytosine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by capillary zone electrophoresis and chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA1102 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD3455
LRAC4363
LRAA9144
LRAA1102

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Development and validation of a procedure for the determination of minoxidil in hair-regrowth formulations using two variants of capillary zone electrophoresis
Patterson SC, et al.
Il Farmaco (Societa Chimica Italiana : 1989), 60(6-7), 547-554 (2005)
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Journal of Pharmaceutical and Biomedical Analysis, 54(5), 1065-1072 (2011)
C P Walsh et al.
Current topics in microbiology and immunology, 301, 283-315 (2006-03-31)
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