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PHR1520

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Chlortetracycline Hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Chlortetracycline hydrochloride, 7-Chlorotetracycline hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C22H23ClN2O8 · HCl
CAS Number:
64-72-2
Molecular Weight:
515.34
Beilstein/REAXYS Number:
3858364
EC Number:
200-591-7
MDL number:
MFCD00082440
UNSPSC Code:
41116107
PubChem Substance ID:
329823435
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

agency

traceable to BP 783
traceable to Ph. Eur. C2000000
traceable to USP 1129007

API family

chlortetracycline

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

210-215 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

-10 to -25°C

SMILES string

Cl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O

InChI

1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1

InChI key

CBHYYLPALVVVEY-LYNLVHCPSA-N

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General description

Chlortetracycline Hydrochloride is a salt of chlortetracycline, which is a tetracycline which shows broad-spectrum antibiotic activity. It is generally used as a veterinary and aquaculture medicine. It is often used on dairy cattle and aquacultured catfish, salmon, and lobster.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Chlortetracycline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3430 in the slot below. This is an example certificate only and may not be the lot that you receive.

related product

Product No.
Description
Pricing

pictograms

Exclamation markHealth hazard
GHS07,GHS08

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD3654
LRAD3241
LRAC3430
LRAA9234
LRAA3327

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Determination of tetracycline residues in shrimp and whole milk using liquid chromatography with ultraviolet detection and residue confirmation by mass spectrometry
Andersen WC, et al.
Analytica Chimica Acta, 529(1-2), 145-150 (2005)
The spectrophotometric assay for chlortetracycline HCl and tetracycline HCl in pharmaceuticals
Chiccarelli FS, et al.
Journal of the American Pharmaceutical Association, 48(5), 263-268 (1959)

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