PHR1737
Colistimethate Sodium
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
Colistimethate sodium, CMS, Colistin sulphomethate sodium
About This Item
Recommended Products
grade
certified reference material
pharmaceutical secondary standard
Quality Level
agency
traceable to Ph. Eur. C2600000
traceable to USP 1147009
API family
colistimethate
CofA
current certificate can be downloaded
packaging
pkg of 500 mg
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
-10 to -25°C
InChI
1S/C58H110N16O28S5.5Na/c1-9-35(6)12-10-11-13-46(77)65-38(14-20-59-28-103(88,89)90)53(82)74-48(37(8)76)58(87)70-41(17-23-62-31-106(97,98)99)50(79)68-43-19-25-64-57(86)47(36(7)75)73-54(83)42(18-24-63-32-107(100,101)102)67-49(78)39(15-21-60-29-104(91,92)93)69-55(84)44(26-33(2)3)72-56(85)45(27-34(4)5)71-52(81)40(66-51(43)80)16-22-61-30-105(94,95)96;;;;;/h33-45,47-48,59-63,75-76H,9-32H2,1-8H3,(H,64,86)(H,65,77)(H,66,80)(H,67,78)(H,68,79)(H,69,84)(H,70,87)(H,71,81)(H,72,85)(H,73,83)(H,74,82)(H,88,89,90)(H,91,92,93)(H,94,95,96)(H,97,98,99)(H,100,101,102);;;;;/q;5*+1/p-5
InChI key
IQWHCHZFYPIVRV-UHFFFAOYSA-I
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General description
Colistimethate Sodium belongs to the class of polymyxin antibiotics that acts by inhibiting the Gram negative bacteria. It is a prodrug that can hydrolyze to colistin in vivo or in vitro. It is employed as a last resort antibiotic to treat Pseudomonas aeruginosa infection in cystic fibrosis patients.
Application
Analysis Note
Other Notes
Footnote
related product
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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