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PHR1812

Supelco

Tranexamic acid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

trans-4-(Aminomethyl)cyclohexanecarboxylic acid, AMCA, AMCHA, HAKU, TAMCHA, Tranexamic acid

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About This Item

Linear Formula:
H2NCH2C6H10CO2H
CAS Number:
1197-18-8
Molecular Weight:
157.21
Beilstein/REAXYS Number:
2207452
EC Number:
214-818-2
MDL number:
MFCD00001466
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

agency

traceable to Ph. Eur. T1810000
traceable to USP 1672745

description

Pharmaceutical Secondary Standard; Certified Reference Material

API family

tranexamic acid

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

>300 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

NC[C@H]1CC[C@@H](CC1)C(O)=O

InChI

1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-

InChI key

GYDJEQRTZSCIOI-LJGSYFOKSA-N

Gene Information

human ... PLG(5340)

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General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Tranexamic acid may be used as a pharmaceutical reference standard for the determination of the analyte in plasma samples, pharmaceutical formulations and cosmetic products by chromatography and spectrophotometry.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2913 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD4438
LRAB8978
LRAC2913
LRAC7790
LRAB8978

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Determination of tranexamic acid in cosmetic products by high-performance liquid chromatography coupled with barrel plating nickel electrode
Shih Y, et al.
Journal of Pharmaceutical and Biomedical Analysis, 48(5), 1446-1450 (2008)
Determination of plasma tranexamic acid using cation-exchange high-performance liquid chromatography with fluorescence detection
Elworthy PM, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 343, 109-117 (1985)
Spectrophotometric and spectrofluorimetric methods for the determination of tranexamic acid in pharmaceutical formulation
El-Aroud KA, et al.
Chemical & Pharmaceutical Bulletin, 55(3), 364-367 (2007)

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